Effects of Asymmetric Superior Laryngeal Nerve Stimulation on Glottic Posture, Acoustics, Vibration

Overview

Journal Laryngoscope

Specialty Otorhinolaryngology

Date 2013 May 29

PMID 23712542

Citations 25

Authors

Dinesh K Chhetri

Juergen Neubauer

Jennifer L Bergeron

Elazar Sofer

Kevin A Peng

Nausheen Jamal

Affiliations

Soon will be listed here.

Abstract

Objectives/hypothesis: Evaluate the effects of asymmetric superior laryngeal nerve stimulation on the vibratory phase, laryngeal posture, and acoustics.

Study Design: Basic science study using an in vivo canine model.

Methods: The superior laryngeal nerves were symmetrically and asymmetrically stimulated over eight activation levels to mimic laryngeal asymmetries representing various levels of superior laryngeal nerve paresis and paralysis conditions. Glottal posture change, vocal fold speed, and vibration of these 64 distinct laryngeal-activation conditions were evaluated by high speed video and concurrent acoustic and aerodynamic recordings. Assessments were made at phonation onset.

Results: Vibratory phase was symmetric in all symmetric activation conditions, but consistent phase asymmetry toward the vocal fold with higher superior laryngeal-nerve activation was observed. Superior laryngeal nerve paresis and paralysis conditions had reduced vocal fold strain and fundamental frequency. Superior laryngeal nerve activation increased vocal fold closure speed, but this effect was more pronounced for the ipsilateral vocal fold. Increasing asymmetry led to aperiodic and chaotic vibration.

Conclusions: This study directly links vocal-fold tension asymmetry with vibratory phase asymmetry, in particular the side with greater tension leads in the opening phase. The clinical observations of vocal fold lag, reduced vocal range, and aperiodic voice in superior laryngeal paresis and paralysis is also supported.

Citing Articles

Simultaneous High-Speed Video Laryngoscopy and Acoustic Aerodynamic Recordings during Vocal Onset of Variable Sound Pressure Level: A Preliminary Study.

Woo P Bioengineering (Basel). 2024; 11(4).

PMID: 38671756 PMC: 11048587. DOI: 10.3390/bioengineering11040334.

Aerodynamic Performance and Neuromuscular Control in Patients with Unilateral Vocal Fold Paralysis.

Chung W, Liu K, Chuang H, Lu Y, Li H, Wong A Diagnostics (Basel). 2022; 12(12).

PMID: 36553131 PMC: 9777229. DOI: 10.3390/diagnostics12123124.

Persistence of lower vocal intensity in vocal fold paralysis with cricothyroid impairment after hyaluronate injection.

Liu K, Lu Y, Chuang H, Hsin L, Lin W, Wong A Laryngoscope Investig Otolaryngol. 2022; 7(6):1922-1929.

PMID: 36544927 PMC: 9764743. DOI: 10.1002/lio2.927.

Control of Pre-phonatory Glottal Shape by Intrinsic Laryngeal Muscles.

Pillutla P, Reddy N, Schlegel P, Zhang Z, Chhetri D Laryngoscope. 2022; 133(7):1690-1697.

PMID: 36129162 PMC: 10027621. DOI: 10.1002/lary.30403.

Analysis of vibratory mode changes in symmetric and asymmetric activation of the canine larynx.

Schlegel P, Berry D, Chhetri D PLoS One. 2022; 17(4):e0266910.

PMID: 35421159 PMC: 9009716. DOI: 10.1371/journal.pone.0266910.

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