Whole Genome Expression of Cellular Response to Stroke

Overview

Journal Stroke

Specialties Cardiology & Vascular Diseases
Neurology

Date 2013 May 28

PMID 23709718

Citations 10

Authors

Frank R Sharp

Glen C Jickling

Affiliations

Soon will be listed here.

Citing Articles

Navi B, Mathias R, Sherman C, Wolfe J, Kamel H, Tagawa S Stroke. 2019; 50(11):3259-3264.

PMID: 31510897 PMC: 6817410. DOI: 10.1161/STROKEAHA.119.026143.

Transcriptional Response and Morphological Features of the Neurovascular Unit and Associated Extracellular Matrix After Experimental Stroke in Mice.

Aleithe S, Blietz A, Mages B, Hobusch C, Hartig W, Michalski D Mol Neurobiol. 2019; 56(11):7631-7650.

PMID: 31089963 PMC: 6815284. DOI: 10.1007/s12035-019-1604-4.

Blood Biomarkers for Stroke Diagnosis and Management.

Kamtchum-Tatuene J, Jickling G Neuromolecular Med. 2019; 21(4):344-368.

PMID: 30830566 PMC: 6722038. DOI: 10.1007/s12017-019-08530-0.

Hyperacute changes in blood mRNA expression profiles of rats after middle cerebral artery occlusion: Towards a stroke time signature.

Dagonnier M, Wilson W, Favaloro J, Rewell S, Lockett L, Sastra S PLoS One. 2018; 13(11):e0206321.

PMID: 30439964 PMC: 6237327. DOI: 10.1371/journal.pone.0206321.

The intracerebral hemorrhage blood transcriptome in humans differs from the ischemic stroke and vascular risk factor control blood transcriptomes.

Stamova B, Ander B, Jickling G, Hamade F, Durocher M, Zhan X J Cereb Blood Flow Metab. 2018; 39(9):1818-1835.

PMID: 29651892 PMC: 6727143. DOI: 10.1177/0271678X18769513.

References

Jickling G, Xu H, Stamova B, Ander B, Zhan X, Tian Y . Signatures of cardioembolic and large-vessel ischemic stroke. Ann Neurol. 2010; 68(5):681-92. PMC: 2967466. DOI: 10.1002/ana.22187. View

Moore D, Li H, Jeffries N, Wright V, Cooper Jr R, Elkahloun A . Using peripheral blood mononuclear cells to determine a gene expression profile of acute ischemic stroke: a pilot investigation. Circulation. 2005; 111(2):212-21. DOI: 10.1161/01.CIR.0000152105.79665.C6. View

Barr T, Conley Y, Ding J, Dillman A, Warach S, Singleton A . Genomic biomarkers and cellular pathways of ischemic stroke by RNA gene expression profiling. Neurology. 2010; 75(11):1009-14. PMC: 2942033. DOI: 10.1212/WNL.0b013e3181f2b37f. View

Tang Y, Nee A, Lu A, Ran R, Sharp F . Blood genomic expression profile for neuronal injury. J Cereb Blood Flow Metab. 2003; 23(3):310-9. DOI: 10.1097/01.WCB.0000048518.34839.DE. View

Tang Y, Lu A, Aronow B, Sharp F . Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: blood genomic fingerprints of disease. Ann Neurol. 2002; 50(6):699-707. DOI: 10.1002/ana.10042. View

Jickling G, Stamova B, Ander B, Zhan X, Liu D, Sison S . Prediction of cardioembolic, arterial, and lacunar causes of cryptogenic stroke by gene expression and infarct location. Stroke. 2012; 43(8):2036-41. PMC: 3422649. DOI: 10.1161/STROKEAHA.111.648725. View

Zhan X, Jickling G, Tian Y, Stamova B, Xu H, Ander B . Transient ischemic attacks characterized by RNA profiles in blood. Neurology. 2011; 77(19):1718-24. PMC: 3208953. DOI: 10.1212/WNL.0b013e318236eee6. View

Xu H, Stamova B, Jickling G, Tian Y, Zhan X, Ander B . Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brain. Stroke. 2010; 41(12):2744-9. PMC: 3694808. DOI: 10.1161/STROKEAHA.110.591875. View

Zhan X, Kim C, Sharp F . Very brief focal ischemia simulating transient ischemic attacks (TIAs) can injure brain and induce Hsp70 protein. Brain Res. 2008; 1234:183-97. PMC: 2670998. DOI: 10.1016/j.brainres.2008.07.094. View

10.

Montaner J . Blood biomarkers to guide stroke thrombolysis. Front Biosci (Elite Ed). 2009; 1(1):200-8. DOI: 10.2741/E19. View

11.

Sharp F, Jickling G, Stamova B, Tian Y, Zhan X, Liu D . Molecular markers and mechanisms of stroke: RNA studies of blood in animals and humans. J Cereb Blood Flow Metab. 2011; 31(7):1513-31. PMC: 3137473. DOI: 10.1038/jcbfm.2011.45. View

12.

Zhan X, Ander B, Jickling G, Turner R, Stamova B, Xu H . Brief focal cerebral ischemia that simulates transient ischemic attacks in humans regulates gene expression in rat peripheral blood. J Cereb Blood Flow Metab. 2009; 30(1):110-8. PMC: 2949112. DOI: 10.1038/jcbfm.2009.189. View

13.

Jickling G, Zhan X, Stamova B, Ander B, Tian Y, Liu D . Ischemic transient neurological events identified by immune response to cerebral ischemia. Stroke. 2012; 43(4):1006-12. PMC: 3327404. DOI: 10.1161/STROKEAHA.111.638577. View

14.

Xu H, Tang Y, Liu D, Ran R, Ander B, Apperson M . Gene expression in peripheral blood differs after cardioembolic compared with large-vessel atherosclerotic stroke: biomarkers for the etiology of ischemic stroke. J Cereb Blood Flow Metab. 2008; 28(7):1320-8. DOI: 10.1038/jcbfm.2008.22. View

15.

Whiteley W, Chong W, Sengupta A, Sandercock P . Blood markers for the prognosis of ischemic stroke: a systematic review. Stroke. 2009; 40(5):e380-9. DOI: 10.1161/STROKEAHA.108.528752. View

16.

Stamova B, Xu H, Jickling G, Bushnell C, Tian Y, Ander B . Gene expression profiling of blood for the prediction of ischemic stroke. Stroke. 2010; 41(10):2171-7. PMC: 2987675. DOI: 10.1161/STROKEAHA.110.588335. View

17.

Jensen M, Chacon M, Sattin J, Levine R, Vemuganti R . Potential biomarkers for the diagnosis of stroke. Expert Rev Cardiovasc Ther. 2009; 7(4):389-93. DOI: 10.1586/erc.09.9. View

18.

Baird A . Blood genomics in human stroke. Stroke. 2007; 38(2 Suppl):694-8. DOI: 10.1161/01.STR.0000250431.99687.7b. View

19.

Jickling G, Stamova B, Ander B, Zhan X, Tian Y, Liu D . Profiles of lacunar and nonlacunar stroke. Ann Neurol. 2011; 70(3):477-85. PMC: 3201749. DOI: 10.1002/ana.22497. View

20.

Tang Y, Xu H, Du X, Lit L, Walker W, Lu A . Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study. J Cereb Blood Flow Metab. 2006; 26(8):1089-102. DOI: 10.1038/sj.jcbfm.9600264. View