and Gastric Inflammation: Role of MUC1 Mucin

Overview

Journal J Pediatr Biochem

Publisher Thieme

Specialty Biochemistry

Date 2013 May 14

PMID 23667410

Citations 4

Authors

Erik P Lillehoj

Wei Guang

Hua Ding

Steven J Czinn

Thomas G Blanchard

Affiliations

Soon will be listed here.

Abstract

More than half of the world's population is infected with , which is strongly linked to the development of chronic gastric inflammation (gastritis), peptic ulcer disease, and stomach cancer. However, for unknown reasons, the vast majority of infected individuals are asymptomatic beyond histologic inflammation. This review article will summarize current knowledge on the molecular mechanisms of colonization of the gastric mucosa, with a particular focus on the biochemistry of MUC1 mucin in the host response to bacterial infection.

Citing Articles

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PMID: 39564479 PMC: 11573778. DOI: 10.3389/fmicb.2024.1462220.

Association between MUC1 rs4072037 polymorphism and in patients with gastric cancer.

Shekarriz R, Jabbari H, Alikhani R, Alizadeh-Navaei R, Hashemi-Soteh M Caspian J Intern Med. 2024; 15(1):132-140.

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Radziejewska I, Borzym-Kluczyk M, Leszczynska K Biomed Rep. 2020; 14(2):19.

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