[Normocalcemic Primary Hyperparathyroidism: Recommendations for Management and Follow-up]

Objective: To provide practical recommendations for evaluation and follow-up of patients with normocalcemic primary hyperparathyroidism.

Participants: Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology.

Methods: A systematic search was made in MEDLINE (PubMed), using the terms normocalcemic primary hyperparathyroidism and primary hyperparathyroidism, for articles in English published before 22 November 2012. Literature was reviewed by 2 members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology, and after development of recommendations, the manuscript was reviewed by all other members of the Group, and their suggestions were incorporated.

Conclusions: The document provides practical recommendations for evaluation and follow-up of patients with normocalcemic primary hyperparathyroidism. There is however little evidence available about different aspects of this disease, mainly progression rate and clinical impact. More data are therefore needed before definite recommendations may be made.