Is There an Epidemic Vitamin D Deficiency in German Orthopaedic Patients?

Overview

Journal Clin Orthop Relat Res

Publisher Wolters Kluwer

Specialty Orthopedics

Date 2013 Apr 24

PMID 23609810

Citations 17

Authors

Gerrit Steffen Maier

Philipp Jakobs

Klaus Edgar Roth

Andreas Alois Kurth

Uwe Maus

Affiliations

Soon will be listed here.

Abstract

Background: Vitamin D plays an essential role in bone health and muscle function. Some studies have shown a widespread rate of vitamin D deficiency in the general population, but few have reported on the vitamin D status of orthopaedic patients.

Questions/purposes: We investigated (1) the extent of hypovitaminosis D in orthopaedic patients, (2) seasonal variations in vitamin D levels, and (3) possible risk factors for insufficient vitamin D levels.

Methods: Vitamin D levels in 1119 patients consecutively admitted to an orthopaedic surgery department in 2011 were measured. To investigate the correlation between climate factors and vitamin D levels, the sunshine hours for each month in 2011 were collected by Deutscher Wetterdienst (the German weather service) in the region where most tested patients lived. The prevalence of normal (> 30 ng/mL), insufficient (20-30 ng/mL), and deficient (< 20 ng/mL) 25-hydroxyvitamin D levels was determined. Univariate and multivariate analyses were used to assess risk factors for insufficient vitamin D levels.

Results: Overall, 84% of patients had insufficient levels of vitamin D and 60% were vitamin D deficient. Only 15% were in the target range of 30 to 60 ng/mL. The prevalence of low vitamin D levels was greater during winter and months with fewer sunshine hours. Vitamin D levels did not vary according to age, sex, and disease. Individuals with obesity, hypertension, and osteoporosis were more likely to have low vitamin D levels compared with their healthy counterparts.

Conclusions: There is an alarmingly high rate of hypovitaminosis D and vitamin D deficiency among orthopaedic patients in this region of Germany, whose latitude (50° N) is approximately the same as those of Vancouver (49°, 15' N) and Paris (48°, 51' N). Given the well-known effects on bone metabolism and muscle health, low vitamin D levels may negatively affect patients. Screening and treating hypovitaminosis D appears to be important in this patient population.

Citing Articles

Vitamin D and Albumin Deficiency in a Swiss Orthopaedic Surgery In-Patient Cohort.

Kingston C, Santini S, Hauke D, Valderrabano V J Clin Med. 2024; 13(9).

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The role of vitamin D and vitamin D deficiency in orthopaedics and traumatology-a narrative overview of the literature.

Maier G, Weissenberger M, Rudert M, Roth K, Horas K Ann Transl Med. 2021; 9(11):942.

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Vitamin D and COVID-19: Can it be protective?.

Weiss S Am J Clin Nutr. 2021; 113(5):1079-1080.

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The Relationship Between Serum 25[OH]D Concentration and Orthopaedic Infection: A Case-Control Study.

Zargaran A, Zargaran D, Trompeter A Orthop Res Rev. 2020; 12:121-125.

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Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control study.

Choi W, Kim J, Byun S, Ryu H, Rojas D BMC Musculoskelet Disord. 2020; 21(1):251.

PMID: 32303230 PMC: 7165410. DOI: 10.1186/s12891-020-03295-1.

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