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Fluconazole Levels in Plasma and Vaginal Secretions of Patients After a 150-milligram Single Oral Dose and Rate of Eradication of Infection in Vaginal Candidiasis

Overview
Journal Antimicrob Agents Chemother
Publisher American Society for Microbiology
Specialty Pharmacology
Date 1990 May 1
PMID 2360828
Citations 23
Authors
E T Houang
O Chappatte
D Byrne
P V Macrae
J E Thorpe
Affiliations
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Abstract

Mean peak concentrations of fluconazole in plasma and vaginal secretions of females after a 150-mg single oral dose were shown to be 2.82 micrograms/ml and 2.43 micrograms/g, respectively. Our results indicate that clinically efficacious concentrations of fluconazole in vaginal secretions are easily achieved after this single oral dose.

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References
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