HIV/AIDS, Comorbidity, and Alcohol: Can We Make a Difference?

Overview

Journal Alcohol Res Health

Specialty Psychiatry

Date 2013 Apr 16

PMID 23584067

Citations 35

Authors

Amy Justice

Lynn Sullivan

David Fiellin

Affiliations

Soon will be listed here.

Abstract

Alcohol use is common among people infected with HIV and plays an important role in their health outcomes. Because alcohol use complicates HIV infection and contributes to comorbid diseases, it is important for researchers and practitioners to understand these interactions and to integrate alcohol treatment with medical management of long-term HIV infection and associated comorbidity. The Veterans Aging Cohort Study (VACS) is a large, multisite study of the effects of alcohol use on HIV outcomes in the broader context of aging. A multilevel strategy intervention trial is needed to address the many modifiable implications of alcohol consumption among those receiving treatment for HIV.

Citing Articles

Association of circulating adipokines with metabolic measures among people with HIV: Moderating effects of alcohol use.

Simon L, Lin H, Poret J, Stouwe C, Ferguson T, Welsh D Alcohol Clin Exp Res (Hoboken). 2024; 48(12):2281-2293.

PMID: 39424415 PMC: 11631649. DOI: 10.1111/acer.15464.

Reasons for not seeking alcohol treatment among a sample of Florida adults with HIV who perceived the need for treatment.

Parisi C, Siuluta N, Canidate S, Cook R, Wang Y, Widmeyer M Addict Sci Clin Pract. 2024; 19(1):71.

PMID: 39367510 PMC: 11452928. DOI: 10.1186/s13722-024-00491-5.

Provider perceptions of young people living with HIV and unhealthy alcohol use in Southwestern Uganda: a qualitative study.

Odokonyero R, Nakasujja N, Turiho A, Sanyu N, Muyindike W, Nansera D Addict Sci Clin Pract. 2024; 19(1):62.

PMID: 39223677 PMC: 11370108. DOI: 10.1186/s13722-024-00495-1.

Negative Lifestyle Factors Specific to Aging Persons Living with HIV and Multimorbidity.

Smith W J Int Assoc Provid AIDS Care. 2024; 23:23259582241245228.

PMID: 39051608 PMC: 11273731. DOI: 10.1177/23259582241245228.

Gut microbiome and cardiometabolic comorbidities in people living with HIV.

Troseid M, Nielsen S, Vujkovic-Cvijin I Microbiome. 2024; 12(1):106.

PMID: 38877521 PMC: 11177534. DOI: 10.1186/s40168-024-01815-y.

References

Desquilbet L, Jacobson L, Fried L, Phair J, Jamieson B, Holloway M . HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty. J Gerontol A Biol Sci Med Sci. 2007; 62(11):1279-86. DOI: 10.1093/gerona/62.11.1279. View

Clifford P, Maisto S, Davis C . Alcohol treatment research assessment exposure subject reactivity effects: part I. Alcohol use and related consequences. J Stud Alcohol Drugs. 2007; 68(4):519-28. DOI: 10.15288/jsad.2007.68.519. View

Justice A, Zingmond D, Gordon K, Fultz S, Goulet J, King Jr J . Drug toxicity, HIV progression, or comorbidity of aging: does tipranavir use increase the risk of intracranial hemorrhage?. Clin Infect Dis. 2008; 47(9):1226-30. DOI: 10.1086/592302. View

Freiberg M, Cheng D, Kraemer K, Saitz R, Kuller L, Samet J . The association between hepatitis C infection and prevalent cardiovascular disease among HIV-infected individuals. AIDS. 2007; 21(2):193-7. PMC: 1805683. DOI: 10.1097/QAD.0b013e3280118a0d. View

. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet. 2008; 372(9635):293-9. PMC: 3130543. DOI: 10.1016/S0140-6736(08)61113-7. View

Conen D, Tedrow U, Cook N, Moorthy M, Buring J, Albert C . Alcohol consumption and risk of incident atrial fibrillation in women. JAMA. 2008; 300(21):2489-96. PMC: 2630715. DOI: 10.1001/jama.2008.755. View

Bedimo R, McGinnis K, Dunlap M, Rodriguez-Barradas M, Justice A . Incidence of non-AIDS-defining malignancies in HIV-infected versus noninfected patients in the HAART era: impact of immunosuppression. J Acquir Immune Defic Syndr. 2009; 52(2):203-8. PMC: 2814969. DOI: 10.1097/QAI.0b013e3181b033ab. View

Braithwaite R, McGinnis K, Conigliaro J, Maisto S, Crystal S, Day N . A temporal and dose-response association between alcohol consumption and medication adherence among veterans in care. Alcohol Clin Exp Res. 2005; 29(7):1190-7. DOI: 10.1097/01.alc.0000171937.87731.28. View

Oursler K, Sorkin J, Smith B, Katzel L . Reduced aerobic capacity and physical functioning in older HIV-infected men. AIDS Res Hum Retroviruses. 2006; 22(11):1113-21. DOI: 10.1089/aid.2006.22.1113. View

10.

Bestilny L, Gill M, Mody C, Riabowol K . Accelerated replicative senescence of the peripheral immune system induced by HIV infection. AIDS. 2000; 14(7):771-80. DOI: 10.1097/00002030-200005050-00002. View

11.

Rees V, Saitz R, Horton N, Samet J . Association of alcohol consumption with HIV sex- and drug-risk behaviors among drug users. J Subst Abuse Treat. 2001; 21(3):129-34. DOI: 10.1016/s0740-5472(01)00190-8. View

12.

Braithwaite R, Conigliaro J, McGinnis K, Maisto S, Bryant K, Justice A . Adjusting alcohol quantity for mean consumption and intoxication threshold improves prediction of nonadherence in HIV patients and HIV-negative controls. Alcohol Clin Exp Res. 2008; 32(9):1645-51. PMC: 3111093. DOI: 10.1111/j.1530-0277.2008.00732.x. View

13.

Braithwaite R, Conigliaro J, Roberts M, Shechter S, Schaefer A, McGinnis K . Estimating the impact of alcohol consumption on survival for HIV+ individuals. AIDS Care. 2007; 19(4):459-66. PMC: 3460376. DOI: 10.1080/09540120601095734. View

14.

Samet J, Freedberg K, Stein M, Lewis R, Savetsky J, Sullivan L . Trillion virion delay: time from testing positive for HIV to presentation for primary care. Arch Intern Med. 1998; 158(7):734-40. DOI: 10.1001/archinte.158.7.734. View

15.

McFadden C, Brensinger C, Berlin J, Townsend R . Systematic review of the effect of daily alcohol intake on blood pressure. Am J Hypertens. 2005; 18(2 Pt 1):276-86. DOI: 10.1016/j.amjhyper.2004.07.020. View

16.

Kuller L, Tracy R, Belloso W, De Wit S, Drummond F, Lane H . Inflammatory and coagulation biomarkers and mortality in patients with HIV infection. PLoS Med. 2008; 5(10):e203. PMC: 2570418. DOI: 10.1371/journal.pmed.0050203. View

17.

Chin-Hong P, Deeks S, Liegler T, Hagos E, Krone M, Grant R . High-risk sexual behavior in adults with genotypically proven antiretroviral-resistant HIV infection. J Acquir Immune Defic Syndr. 2005; 40(4):463-71. DOI: 10.1097/01.qai.0000162238.93988.0c. View

18.

Chakkalakal D . Alcohol-induced bone loss and deficient bone repair. Alcohol Clin Exp Res. 2005; 29(12):2077-90. DOI: 10.1097/01.alc.0000192039.21305.55. View

19.

Kozal M . Drug-resistant human immunodefiency virus. Clin Microbiol Infect. 2009; 15 Suppl 1:69-73. DOI: 10.1111/j.1469-0691.2008.02687.x. View

20.

McGinnis K, Fultz S, Skanderson M, Conigliaro J, Bryant K, Justice A . Hepatocellular carcinoma and non-Hodgkin's lymphoma: the roles of HIV, hepatitis C infection, and alcohol abuse. J Clin Oncol. 2006; 24(31):5005-9. DOI: 10.1200/JCO.2006.05.7984. View