Immobilization Techniques in the Fabrication of Nanomaterial-based Electrochemical Biosensors: a Review

Overview

Journal Sensors (Basel)

Publisher MDPI

Specialty Biotechnology

Date 2013 Apr 13

PMID 23580051

Citations 77

Authors

William Putzbach

Niina J Ronkainen

Affiliations

Soon will be listed here.

Abstract

The evolution of 1st to 3rd generation electrochemical biosensors reflects a simplification and enhancement of the transduction pathway. However, in recent years, modification of the transducer with nanomaterials has become increasingly studied and imparts many advantages. The sensitivity and overall performance of enzymatic biosensors has improved tremendously as a result of incorporating nanomaterials in their fabrication. Given the unique and favorable qualities of gold nanoparticles, graphene and carbon nanotubes as applied to electrochemical biosensors, a consolidated survey of the different methods of nanomaterial immobilization on transducer surfaces and enzyme immobilization on these species is beneficial and timely. This review encompasses modification of enzymatic biosensors with gold nanoparticles, carbon nanotubes, and graphene.

Citing Articles

3D Printing in Biocatalysis and Biosensing: From General Concepts to Practical Applications.

Nyenhuis J, Heuer C, Bahnemann J Chem Asian J. 2024; 19(24):e202400717.

PMID: 39340791 PMC: 11639642. DOI: 10.1002/asia.202400717.

Macromolecule-Nanoparticle-Based Hybrid Materials for Biosensor Applications.

Kuntoji G, Kousar N, Gaddimath S, Sannegowda L Biosensors (Basel). 2024; 14(6).

PMID: 38920581 PMC: 11201996. DOI: 10.3390/bios14060277.

Intelligent Health: Progress and Benefit of Artificial Intelligence in Sensing-Based Monitoring and Disease Diagnosis.

Palavicini G Sensors (Basel). 2023; 23(22).

PMID: 38005442 PMC: 10675666. DOI: 10.3390/s23229053.

Electrochemical Immunosensors Developed for Amyloid-Beta and Tau Proteins, Leading Biomarkers of Alzheimer's Disease.

Sharma A, Angnes L, Sattarahmady N, Negahdary M, Heli H Biosensors (Basel). 2023; 13(7).

PMID: 37504140 PMC: 10377038. DOI: 10.3390/bios13070742.

Multivariate Optimization of Electrochemical Biosensors for the Determination of Compounds Related to Food Safety-A Review.

Fernandez H, Zon M, Maccio S, Alaniz R, Di Tocco A, Carrillo Palomino R Biosensors (Basel). 2023; 13(7).

PMID: 37504093 PMC: 10377565. DOI: 10.3390/bios13070694.

References

Reina A, Jia X, Ho J, Nezich D, Son H, Bulovic V . Large area, few-layer graphene films on arbitrary substrates by chemical vapor deposition. Nano Lett. 2008; 9(1):30-5. DOI: 10.1021/nl801827v. View

Wang J . Electrochemical glucose biosensors. Chem Rev. 2007; 108(2):814-25. DOI: 10.1021/cr068123a. View

Wang J, Musameh M . Enzyme-dispersed carbon-nanotube electrodes: a needle microsensor for monitoring glucose. Analyst. 2004; 128(11):1382-5. DOI: 10.1039/b309928h. View

CLARK Jr L, Lyons C . Electrode systems for continuous monitoring in cardiovascular surgery. Ann N Y Acad Sci. 1962; 102:29-45. DOI: 10.1111/j.1749-6632.1962.tb13623.x. View

Thess , Nikolaev , Dai , PETIT , Robert , Xu . Crystalline Ropes of Metallic Carbon Nanotubes. Science. 1996; 273(5274):483-7. DOI: 10.1126/science.273.5274.483. View

Baj-Rossi C, De Micheli G, Carrara S . Electrochemical detection of anti-breast-cancer agents in human serum by cytochrome P450-coated carbon nanotubes. Sensors (Basel). 2012; 12(5):6520-37. PMC: 3386755. DOI: 10.3390/s120506520. View

Jia J, Wang B, Wu A, Cheng G, Li Z, Dong S . A method to construct a third-generation horseradish peroxidase biosensor: self-assembling gold nanoparticles to three-dimensional sol-gel network. Anal Chem. 2002; 74(9):2217-23. DOI: 10.1021/ac011116w. View

Lin Y, Yu B, Lin W, Lee S, Kuo C, Shyue J . Tailoring the surface potential of gold nanoparticles with self-assembled monolayers with mixed functional groups. J Colloid Interface Sci. 2009; 340(1):126-30. DOI: 10.1016/j.jcis.2009.08.014. View

Njagi J, Andreescu S . Stable enzyme biosensors based on chemically synthesized Au-polypyrrole nanocomposites. Biosens Bioelectron. 2007; 23(2):168-75. DOI: 10.1016/j.bios.2007.03.028. View

10.

Li X, Cai W, An J, Kim S, Nah J, Yang D . Large-area synthesis of high-quality and uniform graphene films on copper foils. Science. 2009; 324(5932):1312-4. DOI: 10.1126/science.1171245. View

11.

Shan C, Yang H, Han D, Zhang Q, Ivaska A, Niu L . Graphene/AuNPs/chitosan nanocomposites film for glucose biosensing. Biosens Bioelectron. 2009; 25(5):1070-4. DOI: 10.1016/j.bios.2009.09.024. View

12.

Harper A, Anderson M . Electrochemical glucose sensors--developments using electrostatic assembly and carbon nanotubes for biosensor construction. Sensors (Basel). 2011; 10(9):8248-74. PMC: 3231221. DOI: 10.3390/s100908248. View

13.

Chen J, Tang J, Yan F, Ju H . A gold nanoparticles/sol-gel composite architecture for encapsulation of immunoconjugate for reagentless electrochemical immunoassay. Biomaterials. 2005; 27(10):2313-21. DOI: 10.1016/j.biomaterials.2005.11.004. View

14.

Liu Y, Yu D, Zeng C, Miao Z, Dai L . Biocompatible graphene oxide-based glucose biosensors. Langmuir. 2010; 26(9):6158-60. DOI: 10.1021/la100886x. View

15.

Novoselov K, Geim A, Morozov S, Jiang D, Zhang Y, Dubonos S . Electric field effect in atomically thin carbon films. Science. 2004; 306(5696):666-9. DOI: 10.1126/science.1102896. View

16.

Park Y, Bold B, Lee W, Jeon M, An K, Jeong S . D-(+)-galactose-conjugated single-walled carbon nanotubes as new chemical probes for electrochemical biosensors for the cancer marker galectin-3. Int J Mol Sci. 2011; 12(5):2946-57. PMC: 3116166. DOI: 10.3390/ijms12052946. View

17.

Liu S, Ju H . Reagentless glucose biosensor based on direct electron transfer of glucose oxidase immobilized on colloidal gold modified carbon paste electrode. Biosens Bioelectron. 2003; 19(3):177-83. DOI: 10.1016/s0956-5663(03)00172-6. View

18.

Jia J, Guan W, Sim M, Li Y, Li H . Carbon Nanotubes Based Glucose Needle-type Biosensor. Sensors (Basel). 2016; 8(3):1712-1718. PMC: 3663019. DOI: 10.3390/s8031712. View

19.

Kang X, Wang J, Wu H, Aksay I, Liu J, Lin Y . Glucose oxidase-graphene-chitosan modified electrode for direct electrochemistry and glucose sensing. Biosens Bioelectron. 2009; 25(4):901-5. DOI: 10.1016/j.bios.2009.09.004. View

20.

Xiao Y, Patolsky F, Katz E, Hainfeld J, Willner I . "Plugging into Enzymes": nanowiring of redox enzymes by a gold nanoparticle. Science. 2003; 299(5614):1877-81. DOI: 10.1126/science.1080664. View