Pedalium Murex Linn (Pedaliaceae) Fruits: a Comparative Antioxidant Activity of Its Different Fractions

Overview

Journal Asian Pac J Trop Biomed

Specialty Tropical Medicine

Date 2013 Apr 10

PMID 23569800

Citations 7

Authors

D K Patel

R Kumar

S K Prasad

S Hemalatha

Affiliations

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Abstract

Objective: To examine the antioxidant activity and total phenolic content of different solvent fractions of Pedalium murex (P. murex) Linn fruits (Family: Pedaliaceae) as well as the correlation between the total antioxidant capacity and total phenolic content.

Methods: In the present study, the antioxidant activities of P. murex were evaluated using six in-vitro assays, namely total antioxidant assay, DPPH assay, reducing power, nitric oxide scavenging, hydrogen peroxide scavenging and deoxyribose scavenging assays, and total phenol contents were also investigated.

Results: The ethyl acetate (EA) fraction was found to have high levels of phenolic content (298.72±2.09 mg GAE/g). The EA fraction exhibit higher total antioxidant capacity, higher percentage of DPPH radical scavenging activity (135.11±2.95µg/mL), nitric oxide (200.57±4.51µg/mL), hydrogen peroxide (217.91±6.12 µg/mL), deoxyribose (250.01±4.68µg/mL) and higher reducing power. Correlation coefficient (r(2) =0.914) was found to be significant between total phenolic content and total antioxidant activity.

Conclusions: In general, the results indicate that the EA fractions are rich in phenolic antioxidants with potent free radical scavenging activity implying their importance to human health.

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References

Matkowski A, Piotrowska M . Antioxidant and free radical scavenging activities of some medicinal plants from the Lamiaceae. Fitoterapia. 2006; 77(5):346-53. DOI: 10.1016/j.fitote.2006.04.004. View

Matkowski A, Zielinska S, Oszmianski J, Lamer-Zarawska E . Antioxidant activity of extracts from leaves and roots of Salvia miltiorrhiza Bunge, S. przewalskii Maxim., and S. verticillata L. Bioresour Technol. 2008; 99(16):7892-6. DOI: 10.1016/j.biortech.2008.02.013. View

Yildirim A, Mavi A, Kara A . Determination of antioxidant and antimicrobial activities of Rumex crispus L. extracts. J Agric Food Chem. 2001; 49(8):4083-9. DOI: 10.1021/jf0103572. View

Zhang Y, Wang Z . Phenolic composition and antioxidant activities of two Phlomis species: A correlation study. C R Biol. 2009; 332(9):816-26. DOI: 10.1016/j.crvi.2009.05.006. View

Shen Q, Zhang B, Xu R, Wang Y, Ding X, Li P . Antioxidant activity in vitro of the selenium-contained protein from the Se-enriched Bifidobacterium animalis 01. Anaerobe. 2010; 16(4):380-6. DOI: 10.1016/j.anaerobe.2010.06.006. View

Singh R, Murthy K, Jayaprakasha G . Studies on the antioxidant activity of pomegranate (Punica granatum) peel and seed extracts using in vitro models. J Agric Food Chem. 2002; 50(1):81-6. DOI: 10.1021/jf010865b. View

Zovko Koncic M, Kremer D, Gruz J, Strnad M, Bisevac G, Kosalec I . Antioxidant and antimicrobial properties of Moltkia petraea (Tratt.) Griseb. flower, leaf and stem infusions. Food Chem Toxicol. 2010; 48(6):1537-42. DOI: 10.1016/j.fct.2010.03.021. View

K Jayaprakasha G, Rao L, Sakariah K . Antioxidant activities of flavidin in different in vitro model systems. Bioorg Med Chem. 2004; 12(19):5141-6. DOI: 10.1016/j.bmc.2004.07.028. View

Wannes W, Mhamdi B, Sriti J, Jemia M, Ouchikh O, Hamdaoui G . Antioxidant activities of the essential oils and methanol extracts from myrtle (Myrtus communis var. italica L.) leaf, stem and flower. Food Chem Toxicol. 2010; 48(5):1362-70. DOI: 10.1016/j.fct.2010.03.002. View

10.

Singh R, Singh S, Kumar S, Arora S . Evaluation of antioxidant potential of ethyl acetate extract/fractions of Acacia auriculiformis A. Cunn. Food Chem Toxicol. 2007; 45(7):1216-23. DOI: 10.1016/j.fct.2007.01.002. View

11.

Gulcin I, Elmastas M, Aboul-Enein H . Determination of antioxidant and radical scavenging activity of Basil (Ocimum basilicum L. Family Lamiaceae) assayed by different methodologies. Phytother Res. 2007; 21(4):354-61. DOI: 10.1002/ptr.2069. View

12.

Tepe B . Antioxidant potentials and rosmarinic acid levels of the methanolic extracts of Salvia virgata (Jacq), Salvia staminea (Montbret & Aucher ex Bentham) and Salvia verbenaca (L.) from Turkey. Bioresour Technol. 2007; 99(6):1584-8. DOI: 10.1016/j.biortech.2007.04.008. View

13.

Srinivasan R, Chandrasekar M, Nanjan M, Suresh B . Antioxidant activity of Caesalpinia digyna root. J Ethnopharmacol. 2007; 113(2):284-91. DOI: 10.1016/j.jep.2007.06.006. View

14.

Zhang Y, Li X, Wang Z . Antioxidant activities of leaf extract of Salvia miltiorrhiza Bunge and related phenolic constituents. Food Chem Toxicol. 2010; 48(10):2656-62. DOI: 10.1016/j.fct.2010.06.036. View