Rapid Induction of an Immune Response in Rat Peyer's Patch After Oral Administration of Enterococcus Faecalis Strain EC-12

Overview

Journal Biosci Biotechnol Biochem

Publisher Oxford University Press

Specialties Biochemistry
Biotechnology

Date 2013 Apr 9

PMID 23563541

Citations 6

Authors

Ryo Inoue

Takamitsu Tsukahara

Noriko Matsukawa

Takumi Watanabe

Wakoto Bukawa

Keizo Nakayama

Kazunari Ushida

Affiliations

Soon will be listed here.

Abstract

A rapid and sharp immune response induced in Peyer's patches (PPs) by a single gavage of a heat-killed Enterococcus faecalis strain EC-12 (EC-12) was demonstrated. EC-12 was observed inside the PPs 2.5 h post administration and induction of TNF-α and CD69 gene expression was observed at the same time. The immune response in PPs disappeared 24 h post administration.

Citing Articles

Dysfunction of the Murine Liver with Aging and Its Improvement with the Continuous Consumption of EC-12.

Makioka-Itaya Y, Inoue R, Tsukahara T Nutrients. 2024; 16(13).

PMID: 38999780 PMC: 11243158. DOI: 10.3390/nu16132031.

Enterococcus faecalis EF-2001 protects DNBS-induced inflammatory bowel disease in mice model.

Choi E, Lee H, Kim W, Han K, Iwasa M, Kobayashi K PLoS One. 2019; 14(2):e0210854.

PMID: 30818368 PMC: 6394946. DOI: 10.1371/journal.pone.0210854.

Stimulation of murine cell-mediated immunity by dietary administration of a cell preparation of strain KH-2 and its possible activity against tumour development in mice.

Tsukahara T, Nakamura S, Romero-Perez G, Ohwaki M, Yanagisawa T, Kan T Biosci Microbiota Food Health. 2018; 37(3):49-57.

PMID: 30094120 PMC: 6081610. DOI: 10.12938/bmfh.17-021.

Preventive Effects of Heat-Killed Enterococcus faecalis Strain EC-12 on Mouse Intestinal Tumor Development.

Miyamoto S, Komiya M, Fujii G, Hamoya T, Nakanishi R, Fujimoto K Int J Mol Sci. 2017; 18(4).

PMID: 28406434 PMC: 5412410. DOI: 10.3390/ijms18040826.

Orally Administered Salacia reticulata Extract Reduces H1N1 Influenza Clinical Symptoms in Murine Lung Tissues Putatively Due to Enhanced Natural Killer Cell Activity.

Romero-Perez G, Egashira M, Harada Y, Tsuruta T, Oda Y, Ueda F Front Immunol. 2016; 7:115.

PMID: 27066007 PMC: 4814808. DOI: 10.3389/fimmu.2016.00115.