Phytochemical and Pharmacological Potential of Acanthus Ilicifolius

Overview

Journal J Pharm Bioallied Sci

Specialty Pharmacology

Date 2013 Apr 6

PMID 23559819

Citations 7

Authors

Dharya Singh

Vidhu Aeri

Affiliations

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Abstract

Acanthus ilicifolius (Acanthaceae) has received considerable attention due to its wide range of secondary metabolites and its traditional usage in Indian and Chinese system of medicine. This plant is reported to be a mangrove. Mangrove survives in the most hostile environment with fluctuating tidal and saline regime. Hence, these plants are considered to be rich sources of steroids, triterpenoids, saponins, flavonoids, alkaloids, and tannins. Present review article is an attempt to cover recent developments in phytochemical and pharmacological potential of drug. Traditionally, the plant has been used for dyspepsia, paralysis, asthsma, headache, rheumatism, and skin diseases. The plant is known as 'Krishnasaireyaka' or 'Karimkurunji', is one of the 9 plants equated to the drug 'Sahachara,' which is used in Ayurvedic medicine for rheumatic complaints. The plant has not been explored to its full potential. The review will be a good reference tool for investigators who wish to work on natural compounds with free radical scavenging activity to combat diseases associated with stress.

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References

Mani Senthil Kumar K, Gorain B, Roy D, Zothanpuia , Samanta S, Pal M . Anti-inflammatory activity of Acanthus ilicifolius. J Ethnopharmacol. 2008; 120(1):7-12. DOI: 10.1016/j.jep.2008.07.024. View

Van Kiem P, Quang T, Huong T, Nhung L, Cuong N, Minh C . Chemical constituents of Acanthus ilicifolius L. and effect on osteoblastic MC3T3E1 cells. Arch Pharm Res. 2008; 31(7):823-9. DOI: 10.1007/s12272-001-1232-3. View

Xie L, Liao Y, Huang Q, Huang M . [Pharmacognostic studies on mangrove Acanthus ilicifolius]. Zhongguo Zhong Yao Za Zhi. 2005; 30(19):1501-3. View

Kanchanapoom T, Kamel M, Kasai R, Yamasaki K, Picheansoonthon C, Hiraga Y . Lignan glucosides from Acanthus ilicifolius. Phytochemistry. 2001; 56(4):369-72. DOI: 10.1016/s0031-9422(00)00362-9. View

Babu B, Shylesh B, Padikkala J . Antioxidant and hepatoprotective effect of Acanthus ilicifolius. Fitoterapia. 2001; 72(3):272-7. DOI: 10.1016/s0367-326x(00)00300-2. View

Agshikar N, Naik V, ABRAHAM G, Reddy C, Naqvo S, Mittal P . Analgesic anti-inflammatory activity of Acanthus illicifolius Linn. Indian J Exp Biol. 1979; 17(11):1257-8. View

Babu B, Shylesh B, Padikkala J . Tumour reducing and anticarcinogenic activity of Acanthus ilicifolius in mice. J Ethnopharmacol. 2001; 79(1):27-33. DOI: 10.1016/s0378-8741(01)00347-6. View

Wu J, Zhang S, Huang J, Xiao Q, Li Q, Long L . New aliphatic alcohol and (Z)-4-coumaric acid glycosides from Acanthus ilicifolius. Chem Pharm Bull (Tokyo). 2003; 51(10):1201-3. DOI: 10.1248/cpb.51.1201. View

Bose S, Bose A . Antimicrobial Activity of Acanthus ilicifolius (L.). Indian J Pharm Sci. 2011; 70(6):821-3. PMC: 3040886. DOI: 10.4103/0250-474X.49134. View

10.

Huo C, Liang H, Tu G, Zhao Y, Lin W . A new 5,11-epoxymegastigmane glucoside from Acanthus ilicifolius. Nat Prod Res. 2008; 22(10):896-900. DOI: 10.1080/14786410701642680. View

11.

Chakraborty T, Bhuniya D, Chatterjee M, Rahaman M, Singha D, Chatterjee B . Acanthus ilicifolius plant extract prevents DNA alterations in a transplantable Ehrlich ascites carcinoma-bearing murine model. World J Gastroenterol. 2007; 13(48):6538-48. PMC: 4611293. DOI: 10.3748/wjg.v13.i48.6538. View

12.

Kapil A, Sharma S, Wahidulla S . Leishmanicidal activity of 2-benzoxazolinone from Acanthus illicifolius in vitro. Planta Med. 1994; 60(2):187-8. DOI: 10.1055/s-2006-959449. View

13.

Wu J, Zhang S, Xiao Q, Li Q, Huang J, Long L . Phenylethanoid and aliphatic alcohol glycosides from Acanthus ilicifolius. Phytochemistry. 2003; 63(4):491-5. DOI: 10.1016/s0031-9422(03)00100-6. View

14.

Kanchanapoom T, Kamel M, Kasai R, Picheansoonthon C, Hiraga Y, Yamasaki K . Benzoxazinoid glucosides from Acanthus ilicifolius. Phytochemistry. 2001; 58(4):637-40. DOI: 10.1016/s0031-9422(01)00267-9. View