Hydroxyapatite-fucoidan Nanocomposites for Bone Tissue Engineering
Overview
Affiliations
Hydroxyapatite (HAp) is the promising biomaterials to construct the article bone from the last two decades. In the present study, we have developed hydroxyapatite-fucoidan (HApF) nanocomposite for bone tissue engineering and subsequently characterized by different analytical techniques for bone graft substitute. The chemical characterization suggested that the prepared nanocomposite HApF have amorphous nature, crystal size between 41 and 153 nm was observed. The biochemical characterization inferred that the prepared nanocomposite were non-toxic and mineralization effect of HApF was observed two times higher then HAp. Hence, HApF is the promising biomaterial and could be used for bone tissue construct.
Yizhong B, Chen F, Jin W, Dai J, Mao G, Song B Commun Biol. 2024; 7(1):1471.
PMID: 39516319 PMC: 11549216. DOI: 10.1038/s42003-024-07097-2.
Gupta D, Martinez D, Puertas-Mejia M, Hearnden V, Reilly G Int J Mol Sci. 2024; 25(4).
PMID: 38396762 PMC: 10889223. DOI: 10.3390/ijms25042085.
Development of a Novel Marine-Derived Tricomposite Biomaterial for Bone Regeneration.
Aslam B, Augustyniak A, Clarke S, McMahon H Mar Drugs. 2023; 21(9).
PMID: 37755086 PMC: 10532529. DOI: 10.3390/md21090473.
Unveiling the secrets of marine-derived fucoidan for bone tissue engineering-A review.
V K A, Udduttula A, Jaiswal A Front Bioeng Biotechnol. 2023; 10:1100164.
PMID: 36698636 PMC: 9868180. DOI: 10.3389/fbioe.2022.1100164.
G V Y, Nagendra A, P S, Chatterjee K, Venkatesan J Mar Drugs. 2022; 20(10).
PMID: 36286414 PMC: 9604642. DOI: 10.3390/md20100589.