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Membranes for the Life Sciences and Their Future Roles in Medicine

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Journal Chin J Chem Eng
Date 2022 Jun 27
PMID 35755178
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Abstract

Since the global outbreak of COVID-19, membrane technology for clinical treatments, including extracorporeal membrane oxygenation (ECMO) and protective masks and clothing, has attracted intense research attention for its irreplaceable abilities. Membrane research and applications are now playing an increasingly important role in various fields of life science. In addition to intrinsic properties such as size sieving, dissolution and diffusion, membranes are often endowed with additional functions as cell scaffolds, catalysts or sensors to satisfy the specific requirements of different clinical applications. In this review, we will introduce and discuss state-of-the-art membranes and their respective functions in four typical areas of life science: artificial organs, tissue engineering, blood diagnosis and medical support. Emphasis will be given to the description of certain specific functions required of membranes in each field to provide guidance for the selection and fabrication of the membrane material. The advantages and disadvantages of these membranes have been compared to indicate further development directions for different clinical applications. Finally, we propose challenges and outlooks for future development.

References
1.
Sussman N, Chong M, Koussayer T, He D, Shang T, Whisennand H . Reversal of fulminant hepatic failure using an extracorporeal liver assist device. Hepatology. 1992; 16(1):60-5. DOI: 10.1002/hep.1840160112. View

2.
Radjenovic J, Petrovic M, Barcelo D . Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor. Anal Bioanal Chem. 2006; 387(4):1365-77. PMC: 1805043. DOI: 10.1007/s00216-006-0883-6. View

3.
Palchesko R, Carrasquilla S, Feinberg A . Natural Biomaterials for Corneal Tissue Engineering, Repair, and Regeneration. Adv Healthc Mater. 2018; 7(16):e1701434. DOI: 10.1002/adhm.201701434. View

4.
Watcharajittanont N, Putson C, Pripatnanont P, Meesane J . Layer-by-layer electrospun membranes of polyurethane/silk fibroin based on mimicking of oral soft tissue for guided bone regeneration. Biomed Mater. 2019; 14(5):055011. DOI: 10.1088/1748-605X/ab3502. View

5.
Awad J, Cloutier R, Fournier L, Major D, Martin L, Masson M . Pumpless respiratory assistance using a membrane oxygenator as an artificial placenta: a preliminary study in newborn and preterm lambs. J Invest Surg. 1995; 8(1):21-30. DOI: 10.3109/08941939509015388. View