Synthesis and Antifungal Evaluation of 7-arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates

Overview

Journal Bioorg Med Chem Lett

Specialty Biochemistry

Date 2013 Mar 5

PMID 23453842

Citations 2

Authors

Chung-Kyu Ryu

Ae Li Song

Jung An Hong

Affiliations

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Abstract

7-Arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Most of tested compounds showed good antifungal activity. The results suggest that those 5,8-dioxo-5,8-dihydroisoquinolines would be potent antifungal agents.

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