Accelerating Biopharmaceutical Development in the Decade of Health Information Technology: Applications of EHRs for Outcomes Research and Clinical Trials Recruitment

Overview

Journal Biotechnol Healthc

Specialty Biotechnology

Date 2013 Feb 9

PMID 23393476

Citations 1

Authors

Michael I Lieberman

Peter Embi

Thomas N Ricciardi

Kevin Tabb

Affiliations

Soon will be listed here.

Abstract

Electronic health records hold vast potential for streamlining patient recruitment for clinical trials and improving outcomes research.

Citing Articles

Demonstrating the value of biologics: a call to action.

Clough J Biotechnol Healthc. 2013; 4(4):33-42.

PMID: 23319932 PMC: 3541855.

References

Papaconstantinou C, Theocharous G, Mahadevan S . An expert system for assigning patients into clinical trials based on Bayesian networks. J Med Syst. 1998; 22(3):189-202. DOI: 10.1023/a:1022667800953. View

Bates D, Gawande A . Improving safety with information technology. N Engl J Med. 2003; 348(25):2526-34. DOI: 10.1056/NEJMsa020847. View

Tu S, Kemper C, Lane N, Carlson R, Musen M . A methodology for determining patients' eligibility for clinical trials. Methods Inf Med. 1993; 32(4):317-25. View

Embi P, Jain A, Clark J, Bizjack S, Hornung R, Harris C . Effect of a clinical trial alert system on physician participation in trial recruitment. Arch Intern Med. 2005; 165(19):2272-7. PMC: 1343501. DOI: 10.1001/archinte.165.19.2272. View

Thompson D, Oberteuffer R, Dorman T . Sepsis alert and diagnostic system: integrating clinical systems to enhance study coordinator efficiency. Comput Inform Nurs. 2003; 21(1):22-6; quiz 27-8. DOI: 10.1097/00024665-200301000-00009. View

Weiner D, Butte A, Hibberd P, Fleisher G . Computerized recruiting for clinical trials in real time. Ann Emerg Med. 2003; 41(2):242-6. DOI: 10.1067/mem.2003.52. View

Carlson R, Tu S, Lane N, Lai T, Kemper C, Musen M . Computer-based screening of patients with HIV/AIDS for clinical-trial eligibility. Online J Curr Clin Trials. 1995; Doc No 179:[3347 words; 32 paragraphs]. View

Gennari J, Sklar D, Silva J . Cross-tool communication: from protocol authoring to eligibility determination. Proc AMIA Symp. 2002; :199-203. PMC: 2243429. View

Melton G, Hripcsak G . Automated detection of adverse events using natural language processing of discharge summaries. J Am Med Inform Assoc. 2005; 12(4):448-57. PMC: 1174890. DOI: 10.1197/jamia.M1794. View

10.

Fink E, Kokku P, Nikiforou S, Hall L, Goldgof D, Krischer J . Selection of patients for clinical trials: an interactive web-based system. Artif Intell Med. 2004; 31(3):241-54. DOI: 10.1016/j.artmed.2004.01.017. View

11.

Afrin L, Oates J, Boyd C, Daniels M . Leveraging of open EMR architecture for clinical trial accrual. AMIA Annu Symp Proc. 2004; :16-20. PMC: 1480210. View

12.

Rindfleisch T, Brutlag D . Directions for clinical research and genomic research into the next decade: implications for informatics. J Am Med Inform Assoc. 1998; 5(5):404-11. PMC: 61320. DOI: 10.1136/jamia.1998.0050404. View

13.

Breitfeld P, Weisburd M, Overhage J, Sledge Jr G, Tierney W . Pilot study of a point-of-use decision support tool for cancer clinical trials eligibility. J Am Med Inform Assoc. 1999; 6(6):466-77. PMC: 61390. DOI: 10.1136/jamia.1999.0060466. View

14.

Ohno-Machado L, Wang S, Mar P, Boxwala A . Decision support for clinical trial eligibility determination in breast cancer. Proc AMIA Symp. 1999; :340-4. PMC: 2232554. View

15.

Musen M, Carlson R, FAGAN L, Deresinski S, Shortliffe E . T-HELPER: automated support for community-based clinical research. Proc Annu Symp Comput Appl Med Care. 1992; :719-23. PMC: 2247986. View

16.

Ash J, Bates D . Factors and forces affecting EHR system adoption: report of a 2004 ACMI discussion. J Am Med Inform Assoc. 2004; 12(1):8-12. PMC: 543830. DOI: 10.1197/jamia.M1684. View

17.

Chapman W, Christensen L, Wagner M, Haug P, Ivanov O, Dowling J . Classifying free-text triage chief complaints into syndromic categories with natural language processing. Artif Intell Med. 2004; 33(1):31-40. DOI: 10.1016/j.artmed.2004.04.001. View

18.

Huang Y, Lowe H, Klein D, Cucina R . Improved identification of noun phrases in clinical radiology reports using a high-performance statistical natural language parser augmented with the UMLS specialist lexicon. J Am Med Inform Assoc. 2005; 12(3):275-85. PMC: 1090458. DOI: 10.1197/jamia.M1695. View

19.

Ash N, Ogunyemi O, Zeng Q, Ohno-Machado L . Finding appropriate clinical trials: evaluating encoded eligibility criteria with incomplete data. Proc AMIA Symp. 2002; :27-31. PMC: 2243370. View