The Physics of Cell Membranes
Overview
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An overview is given of the fundamental physics underlying the self-assembly, molecular organisation and electrical properties of the membranes that envelop living cells. These ultra thin (∼ 6 nm) membranes act as a diffusion barrier between the cell interior (cytoplasm) and the external medium. They consist basically of a bi-molecular film of lipid molecules in which are embedded functional proteins that perform a variety of functions, including energy transduction, signalling, transport of ions (and othermolecules), etc. Some examples are also presented of the fascinating and socially and commercially important applications of membrane biophysics.
Nanoscale dipole dynamics of protein membranes studied by broadband dielectric microscopy.
Gramse G, Schonhals A, Kienberger F Nanoscale. 2019; 11(10):4303-4309.
PMID: 30778459 PMC: 6457197. DOI: 10.1039/c8nr05880f.
Membrane water for probing neuronal membrane potentials and ionic fluxes at the single cell level.
Didier M, Tarun O, Jourdain P, Magistretti P, Roke S Nat Commun. 2018; 9(1):5287.
PMID: 30538243 PMC: 6289965. DOI: 10.1038/s41467-018-07713-w.
Nanoscale mapping of dielectric properties based on surface adhesion force measurements.
Wang Y, Shen Y, Wang X, Shen Z, Li B, Hu J Beilstein J Nanotechnol. 2018; 9:900-906.
PMID: 29600151 PMC: 5870145. DOI: 10.3762/bjnano.9.84.
Microwave measurement of giant unilamellar vesicles in aqueous solution.
Cui Y, Delaney W, Darroudi T, Wang P Sci Rep. 2018; 8(1):497.
PMID: 29323157 PMC: 5764977. DOI: 10.1038/s41598-017-18806-9.
The Effect of Cholesterol on the Dielectric Structure of Lipid Bilayers.
Alobeedallah H, Cornell B, Coster H J Membr Biol. 2017; 251(1):153-161.
PMID: 29188314 DOI: 10.1007/s00232-017-0007-6.