Continuity of the DsRNA Genome of Bluetongue Virus
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Abstract
The duplex RNA genome of bluetongue virus, extracted under acidic conditions with sodium dodecyl sulfate and phenol, is an unfragmented continuous structure. Most genomes appeared as a rosette with 10 loops (genes) emanating from a central crescent- or doughnutshaped area. The genome has a mean length of ca. 10 μm which corresponds to a molecular weight of ca. 23 million.
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Libonati M, Carsana A, Furia A Mol Cell Biochem. 1980; 31(3):147-64.
PMID: 6255310 DOI: 10.1007/BF00225848.
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