» Articles » PMID: 23268520

Management of Varicose Veins and Venous Insufficiency

Overview
Journal JAMA
Specialty General Medicine
Date 2012 Dec 27
PMID 23268520
Citations 48
Authors
Affiliations
Soon will be listed here.
Abstract

Chronic venous disease, reviewed herein, is manifested by a spectrum of signs and symptoms, including cosmetic spider veins, asymptomatic varicosities, large painful varicose veins, edema, hyperpigmentation and lipodermatosclerosis of skin, and ulceration. However, there is no definitive stepwise progression from spider veins to ulcers and, in fact, severe skin complications of varicose veins, even when extensive, are not guaranteed. Treatment options range from conservative (eg, medications, compression stockings, lifestyle changes) to minimally invasive (eg, sclerotherapy or endoluminal ablation), invasive (surgical techniques), and hybrid (combination of ≥1 therapies). Ms L, a 68-year-old woman with varicose veins, is presented. She has had vein problems over the course of her life. Her varicose veins recurred after initial treatment, and she is now seeking guidance regarding her current treatment options.

Citing Articles

One-stop endovenous laser ablation leads to superior outcomes for varicose veins and iliac vein compression.

Chen H, Wang C, Ye S, Wang L, Li X, Kong L Sci Rep. 2025; 15(1):1313.

PMID: 39779899 PMC: 11711424. DOI: 10.1038/s41598-025-85306-6.


Molecular insights into Wnt3a and Wnt5a gene expression in venous insufficiency.

Ageed F, Tifow F, Ibrahim L, Ismael A, Balcioglu O, Ozcem B Mol Biol Rep. 2024; 52(1):53.

PMID: 39680245 DOI: 10.1007/s11033-024-10153-z.


Endothelium Piezo1 deletion alleviates experimental varicose veins by attenuating perivenous inflammation.

Zhao J, Xiong Y, Liu Y, Ling J, Liu S, Wang W Mol Cell Biochem. 2024; .

PMID: 39249600 DOI: 10.1007/s11010-024-05115-9.


Causal relationship between varicose veins and mean corpuscular hemoglobin concentration based on Mendelian randomization study.

Chen S, Zhou H, Liu S, Meng L Thromb J. 2024; 22(1):79.

PMID: 39227935 PMC: 11370081. DOI: 10.1186/s12959-024-00647-y.


The particularities of connective fibers from the wall of varicose veins extirpated by cryostripping.

Parau A, Ceausu A, Gaje N, Olariu S, Raica M Rom J Morphol Embryol. 2024; 65(2):273-278.

PMID: 39020542 PMC: 11384038. DOI: 10.47162/RJME.65.2.14.