» Articles » PMID: 23233435

Metformin-associated Lactic Acidosis (MALA): Case Files of the Einstein Medical Center Medical Toxicology Fellowship

Overview
Journal J Med Toxicol
Publisher Springer
Specialty Toxicology
Date 2012 Dec 13
PMID 23233435
Citations 16
Authors
Affiliations
Soon will be listed here.
Citing Articles

Lentiform Fork Sign Secondary To Metformin-Induced Encephalopathy.

Santos M J Brown Hosp Med. 2025; 4(1):38-40.

PMID: 40027456 PMC: 11864398. DOI: 10.56305/001c.127261.


Metformin-Associated Lactic Acidosis in Individuals Without Chronic Kidney Disease on Therapeutic Dose: A Case Report.

Fukuda M, Hirayu N, Nabeta M, Goto M, Takasu O Cureus. 2023; 15(11):e48683.

PMID: 38090422 PMC: 10714376. DOI: 10.7759/cureus.48683.


Metformin Use in Relation to Clinical Outcomes and Hyperinflammatory Syndrome Among COVID-19 Patients With Type 2 Diabetes: A Propensity Score Analysis of a Territory-Wide Cohort.

Wong C, Lui D, Lui A, Low M, Kwok A, Lau K Front Endocrinol (Lausanne). 2022; 13:810914.

PMID: 35321338 PMC: 8935075. DOI: 10.3389/fendo.2022.810914.


Refractory vasodilatory shock secondary to metformin overdose supported with VA ECMO.

Tallman C, Zhang Y, Black N, Lynch K, Fayed M, Armenian P Toxicol Rep. 2022; 9:64-67.

PMID: 35004183 PMC: 8718576. DOI: 10.1016/j.toxrep.2021.12.010.


Profound Metabolic Acidosis due to Metformin Intoxication Requiring Dialysis.

Hermez K, Dudash-Mion C Case Rep Nephrol. 2021; 2021:9914982.

PMID: 34123445 PMC: 8166500. DOI: 10.1155/2021/9914982.


References
1.
Lu H, Parikh P, Lorber D . Phenformin-associated lactic acidosis due to imported phenformin. Diabetes Care. 1996; 19(12):1449-50. DOI: 10.2337/diacare.19.12.1449. View

2.
Manini A, Kumar A, Olsen D, Vlahov D, Hoffman R . Utility of serum lactate to predict drug-overdose fatality. Clin Toxicol (Phila). 2010; 48(7):730-6. PMC: 4091774. DOI: 10.3109/15563650.2010.504187. View

3.
Harvey B, Hickman C, Hinson G, Ralph T, Mayer A . Severe lactic acidosis complicating metformin overdose successfully treated with high-volume venovenous hemofiltration and aggressive alkalinization. Pediatr Crit Care Med. 2005; 6(5):598-601. DOI: 10.1097/01.pcc.0000162451.47034.4f. View

4.
Peters N, Jay N, Barraud D, Cravoisy A, Nace L, Bollaert P . Metformin-associated lactic acidosis in an intensive care unit. Crit Care. 2008; 12(6):R149. PMC: 2646313. DOI: 10.1186/cc7137. View

5.
Perrone J, Phillips C, Gaieski D . Occult metformin toxicity in three patients with profound lactic acidosis. J Emerg Med. 2008; 40(3):271-5. DOI: 10.1016/j.jemermed.2007.11.055. View