Dissemination of a Carbapenem-resistant Acinetobacter Baumannii Strain Belonging to International Clone II/sequence Type 2 and Harboring a Novel AbaR4-like Resistance Island in Latvia

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2012 Dec 12

PMID 23229482

Citations 15

Authors

Mara Saule

Orjan Samuelsen

Uga Dumpis

Arnfinn Sundsfjord

Aija Karlsone

Arta Balode

Edvins Miklasevics

Nabil Karah

Affiliations

Soon will be listed here.

Abstract

An outbreak of hospital-acquired Acinetobacter baumannii infections, caused by a bla(OXA-23)-positive carbapenem-resistant strain belonging to international clone II/ST2, was detected in Latvia. The strain was partially equipped with the armA gene and the intI1-aacA4-catB8-aadA1-qacEΔ1 class 1 integron. In addition, the strain carried AbaR25, a novel AbaR4-like resistance island of ~46,500 bp containing structures similar to the previously described AbaR22 and Tn6167 islands. AbaR25 was characterized by the occurrence of a second copy of Tn6022a interrupted by Tn2006 carrying the bla(OXA-23) gene.

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