Vaginal Toxic Shock Reaction Triggering Desquamative Inflammatory Vaginitis

Overview

Journal J Low Genit Tract Dis

Specialty Gynecology & Obstetrics

Date 2012 Dec 11

PMID 23222054

Citations 4

Authors

Nigel Pereira

Thomas D Edlind

Patrick M Schlievert

Paul Nyirjesy

Affiliations

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Abstract

Objective: The study aimed to report 2 cases of desquamative inflammatory vaginitis associated with toxic shock syndrome toxin 1 (TSST-1)-producing Staphylococcus aureus strains.

Materials And Methods: Case report of 2 patients, 1 with an acute and 1 with a chronic presentation, diagnosed with desquamative inflammatory vaginitis on the basis of clinical findings and wet mount microscopy. Pretreatment and posttreatment vaginal bacterial and yeast cultures were obtained.

Results: Pretreatment vaginal bacterial cultures from both patients grew TSST-1-producing S. aureus. Subsequent vaginal bacterial culture results after oral antibiotic therapy were negative.

Conclusions: Desquamative inflammatory vaginitis may be triggered through TSST-1-mediated vaginal toxic shock reaction.

Citing Articles

Crosstalk between the Resident Microbiota and the Immune Cells Regulates Female Genital Tract Health.

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The Interaction Between Microorganisms, Metabolites, and Immune System in the Female Genital Tract Microenvironment.

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Pathobionts in the Vaginal Microbiota: Individual Participant Data Meta-Analysis of Three Sequencing Studies.

van de Wijgert J, Verwijs M, Gill A, Borgdorff H, van der Veer C, Mayaud P Front Cell Infect Microbiol. 2020; 10:129.

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Spaulding A, Salgado-Pabon W, Kohler P, Horswill A, Leung D, Schlievert P Clin Microbiol Rev. 2013; 26(3):422-47.

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