Further Investigation of the Mediterranean Sponge Axinella Polypoides: Isolation of a New Cyclonucleoside and a New Betaine

Overview

Journal Mar Drugs

Publisher MDPI

Specialties Biology
Pharmacology

Date 2012 Dec 4

PMID 23203274

Citations 10

Authors

Marialuisa Menna

Anna Aiello

Filomena DAniello

Ernesto Fattorusso

Concetta Imperatore

Paolo Luciano

Rocco Vitalone

Affiliations

Soon will be listed here.

Abstract

An exhaustive exploration into the metabolic content of the Mediterranean sponge Axinella-polypoides resulted in the isolation of the new betaine 5 and the new cyclonucleoside 8. The structures of the new metabolites were elucidated by spectroscopic methods assisted by computational methods. The analysis also provided evidence that the sponge does not elaborate pyrrole-imidazole alkaloids (PIAs) but, interestingly, it was shown to contain two already known cyclodipeptides, compounds 9 (verpacamide A) and 10.

Citing Articles

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