Cost-effectiveness of CT Colonography

Overview

Journal Radiol Clin North Am

Specialty Radiology

Date 2012 Nov 28

PMID 23182509

Citations 14

Authors

Cesare Hassan

Perry J Pickhardt

Affiliations

Soon will be listed here.

Abstract

Simulation modeling is extensively applied to CT colonography (CTC) to define its long-term efficacy and cost-effectiveness for colorectal cancer (CRC) screening. CTC is effective in reducing CRC incidence and mortality (40%-77% and 58%-84%, respectively). Several factors may explain this variability. CTC is cost-effective compared with no screening, indicating that it represents an attractive test noncompliance with the available options. CTC needs to achieve a higher attendance rate or cost less than colonoscopy to be cost-effective relative to colonoscopy. Fortunately, both conditions appear to be achievable if CTC becomes a widely utilized and reimbursed screening tool.

Citing Articles

Colorectal cancer screening: A review of current knowledge and progress in research.

Lopes S, Martins C, Santos I, Teixeira M, Gamito E, Alves A World J Gastrointest Oncol. 2024; 16(4):1119-1133.

PMID: 38660635 PMC: 11037045. DOI: 10.4251/wjgo.v16.i4.1119.

An AI-Based Colonic Polyp Classifier for Colorectal Cancer Screening Using Low-Dose Abdominal CT.

Alkabbany I, Ali A, Mohamed M, Elshazly S, Farag A Sensors (Basel). 2022; 22(24).

PMID: 36560132 PMC: 9782078. DOI: 10.3390/s22249761.

Single CT Appointment for Double Lung and Colorectal Cancer Screening: Is the Time Ripe?.

Mascalchi M, Picozzi G, Puliti D, Gorini G, Mantellini P, Sali L Diagnostics (Basel). 2022; 12(10).

PMID: 36292015 PMC: 9601268. DOI: 10.3390/diagnostics12102326.

Computed tomography colonography versus colonoscopy for detection of colorectal cancer: a diagnostic performance study.

Sha J, Chen J, Lv X, Liu S, Chen R, Zhang Z BMC Med Imaging. 2020; 20(1):51.

PMID: 32423413 PMC: 7236500. DOI: 10.1186/s12880-020-00446-7.

Colon cancer screening with CT colonography: logistics, cost-effectiveness, efficiency and progress.

Obaro A, Burling D, Plumb A Br J Radiol. 2018; 91(1090):20180307.

PMID: 29927637 PMC: 6350489. DOI: 10.1259/bjr.20180307.

References

Hassan C, Hunink M, Laghi A, Pickhardt P, Zullo A, Kim D . Value-of-information analysis to guide future research in colorectal cancer screening. Radiology. 2009; 253(3):745-52. DOI: 10.1148/radiol.2533090234. View

Ladabaum U, Song K, Fendrick A . Colorectal neoplasia screening with virtual colonoscopy: when, at what cost, and with what national impact?. Clin Gastroenterol Hepatol. 2004; 2(7):554-63. DOI: 10.1016/s1542-3565(04)00247-2. View

Khan K, Xiong T, McCafferty I, Riley P, Ismail T, Lilford R . Frequency and impact of extracolonic findings detected at computed tomographic colonography in a symptomatic population. Br J Surg. 2007; 94(3):355-61. DOI: 10.1002/bjs.5498. View

Hassan C, Pickhardt P, Pickhardt P, Laghi A, Kim D, Kim D . Computed tomographic colonography to screen for colorectal cancer, extracolonic cancer, and aortic aneurysm: model simulation with cost-effectiveness analysis. Arch Intern Med. 2008; 168(7):696-705. DOI: 10.1001/archinte.168.7.696. View

Tengs T, Wallace A . One thousand health-related quality-of-life estimates. Med Care. 2000; 38(6):583-637. DOI: 10.1097/00005650-200006000-00004. View

Sonnenberg A, Delco F, Bauerfeind P . Is virtual colonoscopy a cost-effective option to screen for colorectal cancer?. Am J Gastroenterol. 1999; 94(8):2268-74. DOI: 10.1111/j.1572-0241.1999.01304.x. View

Heresbach D, Chauvin P, Hess-Migliorretti A, Riou F, Grolier J, Josselin J . Cost-effectiveness of colorectal cancer screening with computed tomography colonography according to a polyp size threshold for polypectomy. Eur J Gastroenterol Hepatol. 2009; 22(6):716-23. DOI: 10.1097/MEG.0b013e32832c76f6. View

Xiong T, Richardson M, Woodroffe R, Halligan S, Morton D, Lilford R . Incidental lesions found on CT colonography: their nature and frequency. Br J Radiol. 2005; 78(925):22-9. DOI: 10.1259/bjr/67998962. View

Pignone M, Saha S, Hoerger T, Mandelblatt J . Cost-effectiveness analyses of colorectal cancer screening: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2002; 137(2):96-104. DOI: 10.7326/0003-4819-137-2-200207160-00007. View

10.

Winawer S, Zauber A, Ho M, OBrien M, GOTTLIEB L, Sternberg S . Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. N Engl J Med. 1993; 329(27):1977-81. DOI: 10.1056/NEJM199312303292701. View

11.

Segnan N, Armaroli P, Bonelli L, Risio M, Sciallero S, Zappa M . Once-only sigmoidoscopy in colorectal cancer screening: follow-up findings of the Italian Randomized Controlled Trial--SCORE. J Natl Cancer Inst. 2011; 103(17):1310-22. DOI: 10.1093/jnci/djr284. View

12.

Pooler B, Baumel M, Cash B, Moawad F, Riddle M, Patrick A . Screening CT colonography: multicenter survey of patient experience, preference, and potential impact on adherence. AJR Am J Roentgenol. 2012; 198(6):1361-6. PMC: 3689205. DOI: 10.2214/AJR.11.7671. View

13.

Levin B, Lieberman D, McFarland B, Andrews K, Brooks D, Bond J . Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology. 2008; 134(5):1570-95. DOI: 10.1053/j.gastro.2008.02.002. View

14.

Aberle D, Adams A, Berg C, Black W, Clapp J, Fagerstrom R . Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011; 365(5):395-409. PMC: 4356534. DOI: 10.1056/NEJMoa1102873. View

15.

Brenner H, Arndt V, Sturmer T, Stegmaier C, Ziegler H, Dhom G . Long-lasting reduction of risk of colorectal cancer following screening endoscopy. Br J Cancer. 2001; 85(7):972-6. PMC: 2375093. DOI: 10.1054/bjoc.2001.2023. View

16.

Kronborg O, Fenger C, Olsen J, Jorgensen O, Sondergaard O . Randomised study of screening for colorectal cancer with faecal-occult-blood test. Lancet. 1996; 348(9040):1467-71. DOI: 10.1016/S0140-6736(96)03430-7. View

17.

Muller A, Sonnenberg A . Prevention of colorectal cancer by flexible endoscopy and polypectomy. A case-control study of 32,702 veterans. Ann Intern Med. 1995; 123(12):904-10. DOI: 10.7326/0003-4819-123-12-199512150-00002. View

18.

Kim D, Pickhardt P, Taylor A, Leung W, Winter T, Hinshaw J . CT colonography versus colonoscopy for the detection of advanced neoplasia. N Engl J Med. 2007; 357(14):1403-12. DOI: 10.1056/NEJMoa070543. View

19.

Pickhardt P, Hassan C, Halligan S, Marmo R . Colorectal cancer: CT colonography and colonoscopy for detection--systematic review and meta-analysis. Radiology. 2011; 259(2):393-405. PMC: 3079122. DOI: 10.1148/radiol.11101887. View

20.

Ashton H, Buxton M, Day N, Kim L, Marteau T, Scott R . The Multicentre Aneurysm Screening Study (MASS) into the effect of abdominal aortic aneurysm screening on mortality in men: a randomised controlled trial. Lancet. 2002; 360(9345):1531-9. DOI: 10.1016/s0140-6736(02)11522-4. View