Adult-onset Still's Disease Revealed by Perimyocarditis and a Concomitant Reactivation of an EBV Infection

Overview

Journal BMJ Case Rep

Specialty General Medicine

Date 2012 Nov 21

PMID 23166163

Citations 4

Authors

Roderich Meckenstock

Audrey Therby

Geraldine Gibault-Genty

David Khau

Sebastien Monnier

Alix Greder-Belan

Affiliations

Soon will be listed here.

Abstract

We describe a 17-year-old patient presenting perimyocarditis as the initial manifestation of the adult-onset Still's disease. Corticotherapy was rapidly successful but induced major acute hepatitis in relation with Epstein-Barr virus reactivation. After 1 year, even if the global outcome is favourable, a slightly lowered ejection fraction still persists. Former case reports and differential diagnosis with reactive haemophagocytic syndrome would be discussed.

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References

Vandergheynst F, Gosset J, van de Borne P, Decaux G . Myopericarditis revealing adult-onset Still's disease. Acta Clin Belg. 2005; 60(4):205-8. DOI: 10.1179/acb.2005.037. View

Vignes S, Wechsler B, Amoura Z, Papo T, Frances C, Huong D . Intravenous immunoglobulin in adult Still's disease refractory to non-steroidal anti-inflammatory drugs. Clin Exp Rheumatol. 1998; 16(3):295-8. View

Kuek A, Weerakoon A, Ahmed K, Ostor A . Adult-onset Still's disease and myocarditis: successful treatment with intravenous immunoglobulin and maintenance of remission with etanercept. Rheumatology (Oxford). 2007; 46(6):1043-4. DOI: 10.1093/rheumatology/kem066. View

Cavagna L, Caporali R, Epis O, Bobbio-Pallavicini F, Montecucco C . Infliximab in the treatment of adult Still's disease refractory to conventional therapy. Clin Exp Rheumatol. 2001; 19(3):329-32. View

Colina M, Govoni M, Trotta F . Fatal myocarditis in adult-onset Still disease with diffuse intravascular coagulation. Rheumatol Int. 2008; 29(11):1355-7. DOI: 10.1007/s00296-008-0813-3. View

Ben Ghorbel I, Lamloum M, Miled M, Aoun N, Houman M, Pouchot J . [Adult-onset Still's disease revealed by a pericardial tamponade: report of two cases]. Rev Med Interne. 2006; 27(7):546-9. DOI: 10.1016/j.revmed.2006.03.027. View

Hosaka S, Takashina N, Ishikawa A, Kondo H, Kashiwazaki S . Adult Still's disease with myocarditis and peritonitis. Intern Med. 1992; 31(6):812-5. DOI: 10.2169/internalmedicine.31.812. View

Bourgeois P . [Still disease in adults, a systemic disease]. Rev Med Interne. 1996; 17(5):373-4. DOI: 10.1016/0248-8663(96)83736-2. View

Miczke A, Wasniewski M, Straburzynska-Migaj E, Leszczynski P, Ochotny R, Grajek S . [Myocarditis--the first symptom of adult Still's disease]. Kardiol Pol. 2009; 67(8):884-6. View

10.

Sachs R, Talvard O, Lanfranchi J . Myocarditis in adult Still's disease. Int J Cardiol. 1990; 27(3):377-80. DOI: 10.1016/0167-5273(90)90295-g. View

11.

Ohta A, Yamaguchi M, Tsunematsu T, Kasukawa R, Mizushima H, Kashiwagi H . Adult Still's disease: a multicenter survey of Japanese patients. J Rheumatol. 1990; 17(8):1058-63. View

12.

Wouters J, van de Putte L . Adult-onset Still's disease; clinical and laboratory features, treatment and progress of 45 cases. Q J Med. 1986; 61(235):1055-65. View

13.

Jadhav P, Nanayakkara N . Myocarditis in adult onset Stills disease. Int J Rheum Dis. 2010; 12(3):272-4. DOI: 10.1111/j.1756-185X.2009.01423.x. View

14.

Bywaters E . Still's disease in the adult. Ann Rheum Dis. 1971; 30(2):121-33. PMC: 1005739. DOI: 10.1136/ard.30.2.121. View

15.

Durand M, Troyanov Y, Laflamme P, Gregoire G . Macrophage activation syndrome treated with anakinra. J Rheumatol. 2010; 37(4):879-80. DOI: 10.3899/jrheum.091046. View

16.

Kristensen L, Bartosik I . Myocarditis in adult-onset Still's disease despite significant immunosuppressive therapy. Scand J Rheumatol. 2006; 35(4):330-1. DOI: 10.1080/03009740500499492. View

17.

Ward S, Wiselka M, Nicholson K . Still's disease and myocarditis associated with recent mumps infection. Postgrad Med J. 1988; 64(755):693-5. PMC: 2428969. DOI: 10.1136/pgmj.64.755.693. View

18.

Husni M, Maier A, Mease P, Overman S, Fraser P, Gravallese E . Etanercept in the treatment of adult patients with Still's disease. Arthritis Rheum. 2002; 46(5):1171-6. DOI: 10.1002/art.10231. View

19.

Pouchot J, Sampalis J, Beaudet F, Carette S, Decary F, HILL R . Adult Still's disease: manifestations, disease course, and outcome in 62 patients. Medicine (Baltimore). 1991; 70(2):118-36. View

20.

Arlet J, Le T, Marinho A, Amoura Z, Wechsler B, Papo T . Reactive haemophagocytic syndrome in adult-onset Still's disease: a report of six patients and a review of the literature. Ann Rheum Dis. 2006; 65(12):1596-601. PMC: 1798476. DOI: 10.1136/ard.2005.046904. View