[Adult-onset Still's Disease Revealed by a Pericardial Tamponade: Report of Two Cases]
Overview
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Introduction: Adult onset Still's disease is a systemic inflammatory disorder of unknown etiology characterized by the association of a high spiking fever, an evanescent skin rash, arthritis, and hyperleukocytosis. Pericarditis is amongst the most common systemic manifestations of adult onset Still's disease.
Exegesis: We report on two patients with a pericardial tamponade revealing an adult onset Still's disease in a 52-year-old female and a 31-year-old male. Pericardial fluid was bloody in the two cases, and histopathology only disclosed non specific inflammatory changes. Both patients received corticosteroids and outcome was uneventful with a follow-up of 8 years and 12 months, respectively.
Conclusion: Pericardial tamponade is an uncommon clinical feature of adult-onset Still's disease and usually occurs at disease onset. It makes the diagnosis of adult-onset Still's disease difficult as the other disease manifestations are commonly neglected. Adult onset Still's disease should be added to the differential of acute pericarditis and tamponade.
Recurrent Pericarditis in Children and Adolescents.
Tombetti E, Giani T, Brucato A, Cimaz R Front Pediatr. 2019; 7:419.
PMID: 31681717 PMC: 6813188. DOI: 10.3389/fped.2019.00419.
Ocon A, Kwiatkowski A, Peredo-Wende R, Blinkhorn R BMJ Case Rep. 2018; 2018.
PMID: 30115716 PMC: 6101325. DOI: 10.1136/bcr-2018-225517.
Adult-onset Still's disease and cardiac tamponade: a rare association.
Carrilho-Ferreira P, Silva D, Silva M, Andre R, Varela M, Diogo A Tex Heart Inst J. 2015; 42(3):277-80.
PMID: 26175648 PMC: 4473629. DOI: 10.14503/THIJ-14-4101.
Elevated Troponin Serum Levels in Adult Onset Still's Disease.
Manzini C, Brugioni L, Colaci M, Tognetti M, Spinella A, Sebastiani M Case Rep Rheumatol. 2015; 2015:732095.
PMID: 25767733 PMC: 4341859. DOI: 10.1155/2015/732095.
Meckenstock R, Therby A, Gibault-Genty G, Khau D, Monnier S, Greder-Belan A BMJ Case Rep. 2012; 2012.
PMID: 23166163 PMC: 4545114. DOI: 10.1136/bcr.01.2011.3688.