Burkitt Lymphomagenesis Linked to MYC Plus PI3K in Germinal Center B Cells

Overview

Journal Oncotarget

Specialty Oncology

Date 2012 Nov 21

PMID 23164662

Citations 9

Authors

Sandrine Sander

Klaus Rajewsky

Affiliations

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Citing Articles

EBV-Positive Lymphoproliferations of B- T- and NK-Cell Derivation in Non-Immunocompromised Hosts.

Dojcinov S, Fend F, Quintanilla-Martinez L Pathogens. 2018; 7(1).

PMID: 29518976 PMC: 5874754. DOI: 10.3390/pathogens7010028.

Shikonin exerts antitumor activity in Burkitt's lymphoma by inhibiting C-MYC and PI3K/AKT/mTOR pathway and acts synergistically with doxorubicin.

Ni F, Huang X, Chen Z, Qian W, Tong X Sci Rep. 2018; 8(1):3317.

PMID: 29463831 PMC: 5820316. DOI: 10.1038/s41598-018-21570-z.

Clinical utility of recently identified diagnostic, prognostic, and predictive molecular biomarkers in mature B-cell neoplasms.

Onaindia A, Medeiros L, Patel K Mod Pathol. 2017; 30(10):1338-1366.

PMID: 28664939 DOI: 10.1038/modpathol.2017.58.

The dual PI3K/mTOR inhibitor NVP-BEZ235 inhibits proliferation and induces apoptosis of burkitt lymphoma cells.

Li C, Xin P, Xiao H, Zheng Y, Huang Y, Zhu X Cancer Cell Int. 2015; 15:65.

PMID: 26130968 PMC: 4486138. DOI: 10.1186/s12935-015-0213-1.

Genetically engineered mouse models of human B-cell precursor leukemias.

Hauer J, Borkhardt A, Sanchez-Garcia I, Cobaleda C Cell Cycle. 2014; 13(18):2836-46.

PMID: 25486471 PMC: 4613455. DOI: 10.4161/15384101.2014.949137.

References

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Sander S, Calado D, Srinivasan L, Kochert K, Zhang B, Rosolowski M . Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis. Cancer Cell. 2012; 22(2):167-79. PMC: 3432451. DOI: 10.1016/j.ccr.2012.06.012. View

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