Complete Genome Sequence of the Novel Escherichia Coli Phage PhAPEC8

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2012 Nov 3

PMID 23118449

Citations 13

Authors

J Tsonos

E M Adriaenssens

J Klumpp

J-P Hernalsteens

R Lavigne

H De Greve

Affiliations

Soon will be listed here.

Abstract

Bacteriophage phAPEC8 is an Escherichia coli-infecting myovirus, isolated on an avian pathogenic Escherichia coli (APEC) strain. APEC strains cause colibacillosis in poultry, resulting in high mortality levels and important economic losses. Genomic analysis of the 147,737-bp double-stranded DNA phAPEC8 genome revealed that 53% of the 269 encoded proteins are unique to this phage. Its closest relatives include the Salmonella phage PVP-SE1 and the coliphage rv5, with 19% and 18% similar proteins, respectively. As such, phAPEC8 represents a novel, phylogenetically distinct clade within the Myoviridae, with molecular properties suitable for phage therapy applications.

Citing Articles

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