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Tools for Mapping High-throughput Sequencing Data

Overview
Journal Bioinformatics
Specialty Biology
Date 2012 Oct 13
PMID 23060614
Citations 97
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Abstract

Motivation: A ubiquitous and fundamental step in high-throughput sequencing analysis is the alignment (mapping) of the generated reads to a reference sequence. To accomplish this task, numerous software tools have been proposed. Determining the mappers that are most suitable for a specific application is not trivial.

Results: This survey focuses on classifying mappers through a wide number of characteristics. The goal is to allow practitioners to compare the mappers more easily and find those that are most suitable for their specific problem.

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