Cell Signals Influencing Hepatic Fibrosis

Overview

Journal Int J Hepatol

Publisher Wiley

Specialty Gastroenterology

Date 2012 Sep 14

PMID 22973518

Citations 32

Authors

Min Cong

Keiko Iwaisako

Chunyan Jiang

Tatiana Kisseleva

Affiliations

Soon will be listed here.

Abstract

Liver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibrosis. The paper then examines the effects of these signaling pathways on the major cell types in the liver. This will provide insights into the molecular pathophysiology of liver fibrosis and should identify therapeutic targets.

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