Fluorescence Bioimaging with Conjugated Polyelectrolytes

Overview

Journal Nanoscale

Specialty Biotechnology

Date 2012 Sep 12

PMID 22964921

Citations 11

Authors

Guangxue Feng

Dan Ding

Bin Liu

Affiliations

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Abstract

This review summarizes the recent developments in fluorescent conjugated polyelectrolytes (CPEs) in bioimaging. The CPEs discussed include linear-, hyperbranched-, and polyhedral oligomeric silsesquioxanes (POSS)-based derivatives. Originating from their special optical properties, good photostability, low cytotoxicity, ease of bioconjugation and tuneable size, CPEs have shown wide applications in in vitro and in vivo protein and cell imaging, drug tracking and gene delivery. Moreover, some CPEs also possess antibacterial and anticancer characteristics as well as apoptosis imaging functions. Finally, this review discusses the future outlook of CPEs in bioimaging applications.

Citing Articles

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Tuning cell surface charge in with conjugated oligoelectrolytes.

Catania C, Thomas A, Bazan G Chem Sci. 2018; 7(3):2023-2029.

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Ultrasmall Conjugated Polymer Nanoparticles with High Specificity for Targeted Cancer Cell Imaging.

Feng G, Liu J, Liu R, Mao D, Tomczak N, Liu B Adv Sci (Weinh). 2017; 4(9):1600407.

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