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New Neurons for 'survival of the Fittest'

Overview
Specialty Neurology
Date 2012 Sep 6
PMID 22948073
Citations 88
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Abstract

Adult neurogenesis is often considered an archaic trait that has undergone a 'phylogenetic reduction' from amphibian ancestors to humans. However, adult neurogenesis in the hippocampal dentate gyrus might actually be a late-evolved trait. In non-mammals, adult hippocampal neurogenesis is not restricted to the equivalents of the dentate gyrus, which also show different connectivity and functionality compared to their mammalian counterpart. Moving actively in a changing world and dealing with novelty and complexity regulate adult neurogenesis. New neurons might thus provide the cognitive adaptability to conquer ecological niches rich with challenging stimuli.

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