» Articles » PMID: 22870127

Medullary Thyroid Carcinoma: The Third Most Common Thyroid Cancer Reviewed

Overview
Journal Oncol Lett
Specialty Oncology
Date 2012 Aug 8
PMID 22870127
Citations 13
Authors
Affiliations
Soon will be listed here.
Abstract

Medullary thyroid cancer is a type of thyroid cancer of neuroendocrine origin. It occurs in hereditary and sporadic forms, and its aggressive behavior is associated with the clinical presentation and type of RET mutation. Total thyroidectomy remains the ideal choice of treatment. Early diagnosis and treatment are the fundamental for a 100% cure rate. In this study, we present our experience of 3 cases, along with a complete review of the literature derived from a Pubmed Database search.

Citing Articles

The Efficacy and Safety of Anlotinib in the Treatment of Thyroid Cancer: A Systematic Review.

Muntean C, Solomon A, Cipaian R, Vonica R, Butuca A, Gaborean V J Clin Med. 2025; 14(2.

PMID: 39860342 PMC: 11765571. DOI: 10.3390/jcm14020338.


A novel role for nonactin: interfering with G-quadruplex in RET-driven medullary thyroid cancer.

Alqahtani T, Alsubait A, Aloumi M, Alamer A, Alomari G, Alwassil O BMC Cancer. 2024; 24(1):1569.

PMID: 39716145 PMC: 11665027. DOI: 10.1186/s12885-024-13345-9.


Limited Thyroidectomy Achieves Equivalent Survival to Total Thyroidectomy for Early Localized Medullary Thyroid Cancer.

Jishu J, Hussein M, Sadakkadulla S, Baah S, Bashumeel Y, Toraih E Cancers (Basel). 2024; 16(23).

PMID: 39682246 PMC: 11640154. DOI: 10.3390/cancers16234062.


Non-secretory medullary thyroid carcinoma with laryngotracheal invasion: a case report and review of the literature.

Alsalamah S, Althunayan T, Alaraifi A, Alessa M AME Case Rep. 2024; 8:87.

PMID: 39380863 PMC: 11459395. DOI: 10.21037/acr-24-45.


LINC00887 Acts as an Enhancer RNA to Promote Medullary Thyroid Carcinoma Progression by Binding with FOXQ1.

Liu D, Wang W, Wu Y, Qiu Y, Zhang L Curr Cancer Drug Targets. 2024; 24(5):519-533.

PMID: 38804344 DOI: 10.2174/0115680096258716231026063704.


References
1.
Cohen M, Hussain H, Moley J . Inhibition of medullary thyroid carcinoma cell proliferation and RET phosphorylation by tyrosine kinase inhibitors. Surgery. 2002; 132(6):960-6; discussion 966-7. DOI: 10.1067/msy.2002.128562. View

2.
Rufini V, Castaldi P, Treglia G, Perotti G, Gross M, Al-Nahhas A . Nuclear medicine procedures in the diagnosis and therapy of medullary thyroid carcinoma. Biomed Pharmacother. 2007; 62(3):139-46. DOI: 10.1016/j.biopha.2007.07.011. View

3.
Bhattacharyya N . A population-based analysis of survival factors in differentiated and medullary thyroid carcinoma. Otolaryngol Head Neck Surg. 2003; 128(1):115-23. DOI: 10.1067/mhn.2003.2. View

4.
Toledo S, Lourenco Jr D, Santos M, Tavares M, Toledo R, Correia-Deur J . Hypercalcitoninemia is not pathognomonic of medullary thyroid carcinoma. Clinics (Sao Paulo). 2009; 64(7):699-706. PMC: 2710445. DOI: 10.1590/S1807-59322009000700015. View

5.
Clark J, Fridman T, Odell M, Brierley J, Walfish P, Freeman J . Prognostic variables and calcitonin in medullary thyroid cancer. Laryngoscope. 2005; 115(8):1445-50. DOI: 10.1097/01.mlg.0000168114.90852.a6. View