» Articles » PMID: 22843863

Complete Genome Sequence of a Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Variant

Overview
Journal J Virol
Date 2012 Jul 31
PMID 22843863
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

Following the 2006 outbreaks of the highly pathogenic porcine reproductive and respiratory syndrome, the causative agent was identified as the highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV). To investigate whether the HP-PRRSV variant continues circulating and accelerating evolution, we sequenced and analyzed the complete genome of the identified HP-PRRSV field strain SD16. The sequence data indicate that the HP-PRRSV variant continues to prevail and accelerate evolution, especially in the nonstructural protein.

Citing Articles

Discovery of small molecules against porcine reproductive and respiratory syndrome virus replication by targeting NendoU activity.

Zhu J, Lai Y, Cheng M, Dash R, Guo S, Guo J J Virol. 2025; 99(2):e0203424.

PMID: 39745451 PMC: 11852993. DOI: 10.1128/jvi.02034-24.


Evolutionary Dynamics of Type 2 Porcine Reproductive and Respiratory Syndrome Virus by Whole-Genome Analysis.

Guo J, Liu Z, Tong X, Wang Z, Xu S, Chen Q Viruses. 2021; 13(12).

PMID: 34960738 PMC: 8706008. DOI: 10.3390/v13122469.


Development of luciferase-linked antibody capture assay based on luciferase immunoprecipitation systems for antibody detection of porcine reproductive and respiratory syndrome virus.

Li J, Wang G, Yang D, Zhao B, Zhao Y, Liu Y BMC Biotechnol. 2018; 18(1):73.

PMID: 30445953 PMC: 6240198. DOI: 10.1186/s12896-018-0483-5.


MYH9 is an Essential Factor for Porcine Reproductive and Respiratory Syndrome Virus Infection.

Gao J, Xiao S, Xiao Y, Wang X, Zhang C, Zhao Q Sci Rep. 2016; 6:25120.

PMID: 27112594 PMC: 4845007. DOI: 10.1038/srep25120.


Characterization of Two Novel Linear B-Cell Epitopes in the Capsid Protein of Avian Hepatitis E Virus (HEV) That Are Common to Avian, Swine, and Human HEVs.

Wang X, Zhao Q, Dang L, Sun Y, Gao J, Liu B J Virol. 2015; 89(10):5491-501.

PMID: 25741007 PMC: 4442536. DOI: 10.1128/JVI.00107-15.


References
1.
Tong G, Zhou Y, Hao X, Tian Z, An T, Qiu H . Highly pathogenic porcine reproductive and respiratory syndrome, China. Emerg Infect Dis. 2008; 13(9):1434-6. PMC: 2857295. DOI: 10.3201/eid1309.070399. View

2.
Wu J, Chen N, Han W, Cao Z, Deng X, Wang L . Complete genome sequence of an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus. J Virol. 2012; 86(11):6381-2. PMC: 3372184. DOI: 10.1128/JVI.00710-12. View

3.
Cavanagh D . Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch Virol. 1997; 142(3):629-33. View

4.
Beerens N, Snijder E . RNA signals in the 3' terminus of the genome of Equine arteritis virus are required for viral RNA synthesis. J Gen Virol. 2006; 87(Pt 7):1977-1983. DOI: 10.1099/vir.0.81750-0. View

5.
Zhou Z, Li X, Liu Q, Hu D, Yue X, Ni J . Complete genome sequence of two novel Chinese virulent porcine reproductive and respiratory syndrome virus variants. J Virol. 2012; 86(11):6373-4. PMC: 3372213. DOI: 10.1128/JVI.00663-12. View