» Articles » PMID: 22778503

Do Herbal Medicines Have Potential for Managing Snake Bite Envenomation?

Overview
Journal Toxicol Int
Date 2012 Jul 11
PMID 22778503
Citations 18
Authors
Affiliations
Soon will be listed here.
Abstract

Snake envenomation is a global public health problem, with highest incidence in Southeast Asia. Inadequate health services, difficult transportation and consequent delay in antisnake venom administration are the main reasons for high mortality. Adverse drug reactions and inadequate storage conditions limit the use of antisnake venom. The medicinal plants, available locally and used widely by traditional healers, therefore need attention. A wide array of plants and their active principles have been evaluated for pharmacological properties. However, numerous unexplored plants claimed to be antidotes in folklore medicine need to be studied. The present article reviews the current status of various medicinal plants for the management of snake bite.

Citing Articles

Therapeutic itineraries of snakebite victims and antivenom access in southern Mexico.

Vasquez C, Neri Castro E, Carter E PLoS Negl Trop Dis. 2024; 18(7):e0012301.

PMID: 38968299 PMC: 11262687. DOI: 10.1371/journal.pntd.0012301.


Experiences and practices of traditional healers on snakebite treatment and prevention in rural Malawi.

Aron M, Mulwafu M, Mailosi B, Kreuels B, Dullie L, Kachimanga C PLoS Negl Trop Dis. 2023; 17(10):e0011653.

PMID: 37792697 PMC: 10550111. DOI: 10.1371/journal.pntd.0011653.


Three finger toxins of elapids: structure, function, clinical applications and its inhibitors.

Hiremath K, Dodakallanavar J, Sampat G, Patil V, Harish D, Chavan R Mol Divers. 2023; 28(5):3409-3426.

PMID: 37749455 DOI: 10.1007/s11030-023-10734-3.


Health care workers' knowledge on identification, management and treatment of snakebite cases in rural Malawi: A descriptive study.

Aron M, Kachimanga C, Kreuels B, Mailosi B, Sambani C, Matanje B PLoS Negl Trop Dis. 2022; 16(11):e0010841.

PMID: 36409666 PMC: 9678285. DOI: 10.1371/journal.pntd.0010841.


Augmented rescue of macroglobulins by supplementation of anti-snake venom with methanolic extract of in envenomation.

Nayak A, Aithal P, Kumar N, Shenoy S, Roche M 3 Biotech. 2022; 12(11):310.

PMID: 36276455 PMC: 9535073. DOI: 10.1007/s13205-022-03379-w.


References
1.
da Silva A, Coelho A, Simas A, Moraes R, Pinheiro D, Fernandes F . Synthesis and pharmacological evaluation of prenylated and benzylated pterocarpans against snake venom. Bioorg Med Chem Lett. 2003; 14(2):431-5. DOI: 10.1016/j.bmcl.2003.10.044. View

2.
Pithayanukul P, Laovachirasuwan S, Bavovada R, Pakmanee N, Suttisri R . Anti-venom potential of butanolic extract of Eclipta prostrata against Malayan pit viper venom. J Ethnopharmacol. 2004; 90(2-3):347-52. DOI: 10.1016/j.jep.2003.10.014. View

3.
Alam M, Gomes A . Viper venom-induced inflammation and inhibition of free radical formation by pure compound (2-hydroxy-4-methoxy benzoic acid) isolated and purified from anantamul (Hemidesmus indicus R. BR) root extract. Toxicon. 1998; 36(1):207-15. DOI: 10.1016/s0041-0101(97)00070-6. View

4.
Ticli F, Hage L, Cambraia R, Pereira P, Magro A, Fontes M . Rosmarinic acid, a new snake venom phospholipase A2 inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interaction. Toxicon. 2005; 46(3):318-27. DOI: 10.1016/j.toxicon.2005.04.023. View

5.
Mendes M, Oliveira C, Lopes D, F Vale L, Alcantara T, Izidoro L . Anti-snake venom properties of Schizolobium parahyba (Caesalpinoideae) aqueous leaves extract. Phytother Res. 2008; 22(7):859-66. DOI: 10.1002/ptr.2371. View