Placental Expression of Indoleamine 2,3-dioxygenase
Overview
Authors
Affiliations
This review focuses on the placental expression of the tryptophan-degrading enzyme indoleamine 2,3-dioxygenase-1 (IDO1) and its potential roles, which may not only encompass immunosuppression and antimicrobial activity, but also vasodilation based on the endothelial expression on both sides of the feto-maternal interface.
COVID-19. Biology, pathophysiology, and immunology: a pathologist view.
Chilosi M, Doglioni C, Ravaglia C, Piciucchi S, Dubini A, Stefanizzi L Pathologica. 2023; 115(5):248-256.
PMID: 38054899 PMC: 10699332. DOI: 10.32074/1591-951X-954.
Xiao C, Wang Y, Fan Y Evol Bioinform Online. 2022; 18:11769343221112780.
PMID: 35923419 PMC: 9340335. DOI: 10.1177/11769343221112780.
Kudo Y, Koh I, Sugimoto J Int J Tryptophan Res. 2021; 13:1178646920984163.
PMID: 33447047 PMC: 7780199. DOI: 10.1177/1178646920984163.
The Role of B7 Family Molecules in Maternal-Fetal Immunity.
Zhao Y, Zheng Q, Jin L Front Immunol. 2020; 11:458.
PMID: 32265918 PMC: 7105612. DOI: 10.3389/fimmu.2020.00458.
The therapeutic potential of targeting tryptophan catabolism in cancer.
Opitz C, Somarribas Patterson L, Mohapatra S, Dewi D, Sadik A, Platten M Br J Cancer. 2019; 122(1):30-44.
PMID: 31819194 PMC: 6964670. DOI: 10.1038/s41416-019-0664-6.