Recent Progress in Synthetic Biology for Microbial Production of C3-C10 Alcohols

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2012 Jun 16

PMID 22701113

Citations 13

Authors

Edna N Lamsen

Shota Atsumi

Affiliations

Soon will be listed here.

Abstract

The growing need to address current energy and environmental problems has sparked an interest in developing improved biological methods to produce liquid fuels from renewable sources. While microbial ethanol production is well established, higher-chain alcohols possess chemical properties that are more similar to gasoline. Unfortunately, these alcohols (except 1-butanol) are not produced efficiently in natural microorganisms, and thus economical production in industrial volumes remains a challenge. Synthetic biology, however, offers additional tools to engineer synthetic pathways in user-friendly hosts to help increase titers and productivity of these advanced biofuels. This review concentrates on recent developments in synthetic biology to produce higher-chain alcohols as viable renewable replacements for traditional fuel.

Citing Articles

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