Crystalloid Inclusions Reminiscent of Hirano Bodies in Autolyzed Peripheral Nerve of Normal Wistar Rats

Overview

Journal Acta Neuropathol

Specialty Neurology

Date 1979 Aug 1

PMID 225921

Citations 3

Authors

S Yagishita

Y Itoh

T Nakano

Y Ono

N Amano

Affiliations

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Abstract

In a study of experimental autolysis of peripheral nerves of normal Wistar rats, crystalloid inclusions similar to Hirano bodies were observed. They occurred in the nuclei and cytoplasms of Schwann cells and in myelinated axons. They first developed after a 12-h autolysis and increased in number and size with time. Their fine structure, localization, and morphogenesis are discussed in relation to the autolysis of the cellular organelles.

Citing Articles

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The structure analysis of Hirano bodies by digital processing on electron micrographs.

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Elucidation of three-dimensional ultrastructure of Hirano bodies by the quick-freeze, deep-etch and replica method.

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