Antiulcer Activity of Agnitundirasa and Its Comparison with Cimetidine in Shay Rat

Agnitundirasa was tested for antigastric ulcer activity in shay rat model. Oral dose of 10 mg/kg reduced the ulceration in shay rat. With 20mg/kg dose the ulceration was completely absent. The antigastric ulcer activity of agnitundirasa (20 mg/kg) was found to be equal to the effect produced by cimetidine (20 mg/kg). The reduction in gastric acidity was more with cimetidine and the reduction in peptic activity was more with agnitundirasa.