Visible Light-driven NADH Regeneration Sensitized by Proflavine for Biocatalysis

Overview

Journal Chembiochem

Specialty Biochemistry

Date 2012 May 5

PMID 22555876

Citations 7

Authors

Dong Heon Nam

Chan Beum Park

Affiliations

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Abstract

Harvest time: Proflavine drives the reduction of NAD(+) in the presence of a Rh-based electron mediator. Photoregenerated NADH was enzymatically active for oxidation by NADH-dependent L-glutamate dehydrogenase for the synthesis of L-glutamate. This work suggests that proflavine has the potential to become an efficient light-harvesting component in biocatalytic photosynthesis driven by solar energy.

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