Does Treatment Adherence Correlates with Health Related Quality of Life? Findings from a Cross Sectional Study

Overview

Journal BMC Public Health

Publisher Biomed Central

Specialty Public Health

Date 2012 May 2

PMID 22545950

Citations 24

Authors

Fahad Saleem

Mohamed Azmi Hassali

Asrul Akmal Shafie

George A Awad

Muhammad Atif

Noman Ul Haq

Hisham Aljadhey

Maryam Farooqui

Affiliations

Soon will be listed here.

Abstract

Background: Although medication adherence and health-related quality of life (HRQoL) are two different outcome measures, it is believed that adherence to medication leads to an improvement in overall HRQoL. The study aimed to evaluate the association between medication adherence and HRQoL.

Methods: A questionnaire-based cross-sectional study design was undertaken with hypertension patients attending public hospitals in Quetta city, Pakistan. HRQoL was measured by Euroqol EQ-5D. Medication adherence was assessed by the Drug Attitude Inventory. Descriptive statistics was used to tabulate demographic and disease-related information. Spearmans correlation was used to assess the association between the study variables. All analysis was performed using SPSS 17.0.

Results: Among 385 study patients, the mean age (SD) was 39.02 (6.59), with 68.8% of males dominating the entire cohort. The mean (SD) duration of hypertension was 3.010.939years. Forty percent (n=154) had a bachelors degree level of education with 34.8% (n=134) working in the private sector. A negative and weak correlation (0.77) between medication adherence and EQ-5D was reported. In addition, a negative weak correlation (0.120) was observed among medication adherence and EQ-VAS.

Conclusions: Correlations among the study variables were negligible and negative. Hence, there is no apparent relationship between the variables.

Citing Articles

The indirect effect of nonadherence on health-related quality of life in older adults with neurological disorders: implications for clinical endpoints and interventions.

Schonenberg A, Mendorf S, Prell T Front Neurol. 2024; 15:1462478.

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Adherence and Quality of Life in Adult Patients With Haemophilia A, Haemophilia B and Von Willebrand Disease: A National Cross-Sectional Survey.

Clausen C, Funding E, Tolver A, Jarden M Eur J Haematol. 2024; 114(1):164-172.

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Treatment Adherence and Health Status of Patients With COPD Under Treatment With Salmeterol/Fluticasone via the Elpenhaler® Device: The AHEAD Study.

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Using a generic quality of life measure to determine adherence thresholds: a cross-sectional study on older adults with neurological disorders in Germany.

Muhlhammer H, Schonenberg A, Lehmann T, Prell T BMJ Open. 2023; 13(1):e067326.

PMID: 36697046 PMC: 9884900. DOI: 10.1136/bmjopen-2022-067326.

Global Burden, Regional Differences, Trends, and Health Consequences of Medication Nonadherence for Hypertension During 2010 to 2020: A Meta-Analysis Involving 27 Million Patients.

Lee E, Poon P, Yip B, Bo Y, Zhu M, Yu C J Am Heart Assoc. 2022; 11(17):e026582.

PMID: 36056737 PMC: 9496433. DOI: 10.1161/JAHA.122.026582.

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