Monte Carlo Study of the Potential Reduction in Out-of-field Dose Using a Patient-specific Aperture in Pencil Beam Scanning Proton Therapy

Overview

Journal Phys Med Biol

Publisher IOP Publishing

Specialties Biophysics
Nuclear Medicine
Radiology

Date 2012 Apr 20

PMID 22513726

Citations 22

Authors

Stephen J Dowdell

Benjamin Clasie

Nicolas Depauw

Peter Metcalfe

Anatoly B Rosenfeld

Hanne M Kooy

Jacob B Flanz

Harald Paganetti

Affiliations

Soon will be listed here.

Abstract

This study is aimed at identifying the potential benefits of using a patient-specific aperture in proton beam scanning. For this purpose, an accurate Monte Carlo model of the pencil beam scanning (PBS) proton therapy (PT) treatment head at Massachusetts General Hospital (MGH) was developed based on an existing model of the passive double-scattering (DS) system. The Monte Carlo code specifies the treatment head at MGH with sub-millimeter accuracy. The code was configured based on the results of experimental measurements performed at MGH. This model was then used to compare out-of-field doses in simulated DS treatments and PBS treatments. For the conditions explored, the penumbra in PBS is wider than in DS, leading to higher absorbed doses and equivalent doses adjacent to the primary field edge. For lateral distances greater than 10 cm from the field edge, the doses in PBS appear to be lower than those observed for DS. We found that placing a patient-specific aperture at nozzle exit during PBS treatments can potentially reduce doses lateral to the primary radiation field by over an order of magnitude. In conclusion, using a patient-specific aperture has the potential to further improve the normal tissue sparing capabilities of PBS.

Citing Articles

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