Increasing Incidence of Melanoma Among Young Adults: an Epidemiological Study in Olmsted County, Minnesota

Overview

Journal Mayo Clin Proc

Specialty General Medicine

Date 2012 Apr 4

PMID 22469345

Citations 80

Authors

Kurtis B Reed

Jerry D Brewer

Christine M Lohse

Kariline E Bringe

Crystal N Pruitt

Lawrence E Gibson

Affiliations

Soon will be listed here.

Abstract

Objective: To identify the change in the incidence of cutaneous melanoma over time among young adults.

Patients And Methods: Using Rochester Epidemiology Project data, we identified patients aged 18 to 39 years who had a first lifetime diagnosis of melanoma from January 1, 1970, through December 31, 2009, in Olmsted County, Minnesota. Demographic and clinical information, including survival, was abstracted, and estimates of the incidence of melanoma and overall and disease-specific survival were generated.

Results: From 1970 to 2009, the incidence of melanoma increased by 8-fold among young women and 4-fold among young men. Overall and disease-specific survival seemed to improve over time; hazard ratios comparing year of diagnosis with mortality were 0.92 and 0.91, respectively.

Conclusion: The incidence of cutaneous melanoma among young adults is rapidly increasing, especially among women. Continued close monitoring of this high-risk population is necessary.

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References

Gallagher R, Spinelli J, Lee T . Tanning beds, sunlamps, and risk of cutaneous malignant melanoma. Cancer Epidemiol Biomarkers Prev. 2005; 14(3):562-6. DOI: 10.1158/1055-9965.EPI-04-0564. View

Choi K, Lazovich D, Southwell B, Forster J, Rolnick S, Jackson J . Prevalence and characteristics of indoor tanning use among men and women in the United States. Arch Dermatol. 2010; 146(12):1356-61. PMC: 8966465. DOI: 10.1001/archdermatol.2010.355. View

Paterson I, Beer H, Adams Jones D . Under-registration of melanoma in Wales in 1998: use of the capture-recapture method to estimate the 'true' incidence. Melanoma Res. 2001; 11(2):141-5. DOI: 10.1097/00008390-200104000-00008. View

Cokkinides V, Weinstock M, Glanz K, Albano J, Ward E, Thun M . Trends in sunburns, sun protection practices, and attitudes toward sun exposure protection and tanning among US adolescents, 1998-2004. Pediatrics. 2006; 118(3):853-64. DOI: 10.1542/peds.2005-3109. View

Melton 3rd L . History of the Rochester Epidemiology Project. Mayo Clin Proc. 1996; 71(3):266-74. DOI: 10.4065/71.3.266. View

Faries M, Wanek L, Elashoff D, Wright B, Morton D . Predictors of occult nodal metastasis in patients with thin melanoma. Arch Surg. 2010; 145(2):137-42. PMC: 2880665. DOI: 10.1001/archsurg.2009.271. View

Amerio P, Manzoli L, Auriemma M, Carbone A, Proietto G, Angelucci D . Epidemiology and clinical and pathologic characteristics of cutaneous malignant melanoma in Abruzzo (Italy). Int J Dermatol. 2009; 48(7):718-22. DOI: 10.1111/j.1365-4632.2009.03974.x. View

Hall H, Jamison P, Fulton J, Clutter G, Roffers S, Parrish P . Reporting cutaneous melanoma to cancer registries in the United States. J Am Acad Dermatol. 2003; 49(4):624-30. DOI: 10.1067/s0190-9622(03)00885-5. View

Christenson L, Borrowman T, Vachon C, Tollefson M, Otley C, Weaver A . Incidence of basal cell and squamous cell carcinomas in a population younger than 40 years. JAMA. 2005; 294(6):681-90. DOI: 10.1001/jama.294.6.681. View

10.

Clegg L, Feuer E, Midthune D, Fay M, Hankey B . Impact of reporting delay and reporting error on cancer incidence rates and trends. J Natl Cancer Inst. 2002; 94(20):1537-45. DOI: 10.1093/jnci/94.20.1537. View

11.

Berk D, LaBuz E, Dadras S, Johnson D, Swetter S . Melanoma and melanocytic tumors of uncertain malignant potential in children, adolescents and young adults--the Stanford experience 1995-2008. Pediatr Dermatol. 2010; 27(3):244-54. DOI: 10.1111/j.1525-1470.2009.01078.x. View

12.

Ting W, Schultz K, Cac N, Peterson M, Walling H . Tanning bed exposure increases the risk of malignant melanoma. Int J Dermatol. 2008; 46(12):1253-7. DOI: 10.1111/j.1365-4632.2007.03408.x. View

13.

Coelho S, Hearing V . UVA tanning is involved in the increased incidence of skin cancers in fair-skinned young women. Pigment Cell Melanoma Res. 2009; 23(1):57-63. PMC: 2810005. DOI: 10.1111/j.1755-148X.2009.00656.x. View

14.

Merlino L, Sullivan K, Whitaker D, Lynch C . The independent pathology laboratory as a reporting source for cutaneous melanoma incidence in Iowa, 1977-1994. J Am Acad Dermatol. 1997; 37(4):578-85. DOI: 10.1016/s0190-9622(97)70175-0. View

15.

Jemal A, Siegel R, Xu J, Ward E . Cancer statistics, 2010. CA Cancer J Clin. 2010; 60(5):277-300. DOI: 10.3322/caac.20073. View

16.

Robinson J, Rigel D, Amonette R . Trends in sun exposure knowledge, attitudes, and behaviors: 1986 to 1996. J Am Acad Dermatol. 1997; 37(2 Pt 1):179-86. DOI: 10.1016/s0190-9622(97)80122-3. View

17.

Bandi P, Cokkinides V, Weinstock M, Ward E . Sunburns, sun protection and indoor tanning behaviors, and attitudes regarding sun protection benefits and tan appeal among parents of U.S. adolescents-1998 compared to 2004. Pediatr Dermatol. 2010; 27(1):9-18. DOI: 10.1111/j.1525-1470.2009.01074.x. View

18.

Koh H, Clapp R, BARNETT J, Nannery W, Tahan S, Geller A . Systematic underreporting of cutaneous malignant melanoma in Massachusetts. Possible implications for national incidence figures. J Am Acad Dermatol. 1991; 24(4):545-50. DOI: 10.1016/0190-9622(91)70079-h. View

19.

Bleyer A, Barr R . Cancer in young adults 20 to 39 years of age: overview. Semin Oncol. 2009; 36(3):194-206. DOI: 10.1053/j.seminoncol.2009.03.003. View

20.

Ries L, Wingo P, Miller D, Howe H, Weir H, Rosenberg H . The annual report to the nation on the status of cancer, 1973-1997, with a special section on colorectal cancer. Cancer. 2000; 88(10):2398-424. DOI: 10.1002/(sici)1097-0142(20000515)88:10<2398::aid-cncr26>3.0.co;2-i. View