NDM-1-producing Klebsiella Pneumoniae Resistant to Colistin in a French Community Patient Without History of Foreign Travel

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2012 Mar 28

PMID 22450982

Citations 15

Authors

Corinne Arpin

Patrick Noury

Delphine Boraud

Laure Coulange

Alain Manetti

Catherine Andre

Fatima Mzali

Claudine Quentin

Affiliations

Soon will be listed here.

Abstract

A carbapenem-resistant Klebsiella pneumoniae strain, Kp5196, was responsible for an uncomplicated cystitis in a patient living at home and without history of foreign travel. This isolate produced the metallocarbapenemase NDM-1 and was resistant to all antibiotics except tetracyclines and colistin. The K. pneumoniae strain belonged to sequence type ST15, and bla(NDM-1) was carried by a nontypeable conjugative plasmid. Two months later, a similar ST15 isolate, Kp5241, was present in the patient but was additionally colistin resistant.

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