All Night Analysis of Time Interval Between Snores in Subjects with Sleep Apnea Hypopnea Syndrome
Overview
Medical Informatics
Authors
Affiliations
Sleep apnea-hypopnea syndrome (SAHS) is a serious sleep disorder, and snoring is one of its earliest and most consistent symptoms. We propose a new methodology for identifying two distinct types of snores: the so-called non-regular and regular snores. Respiratory sound signals from 34 subjects with different ranges of Apnea-Hypopnea Index (AHI = 3.7-109.9 h(-1)) were acquired. A total number of 74,439 snores were examined. The time interval between regular snores in short segments of the all night recordings was analyzed. Severe SAHS subjects show a shorter time interval between regular snores (p = 0.0036, AHI cp: 30 h(-1)) and less dispersion on the time interval features during all sleep. Conversely, lower intra-segment variability (p = 0.006, AHI cp: 30 h(-1)) is seen for less severe SAHS subjects. Features derived from the analysis of time interval between regular snores achieved classification accuracies of 88.2 % (with 90 % sensitivity, 75 % specificity) and 94.1 % (with 94.4 % sensitivity, 93.8 % specificity) for AHI cut-points of severity of 5 and 30 h(-1), respectively. The features proved to be reliable predictors of the subjects' SAHS severity. Our proposed method, the analysis of time interval between snores, provides promising results and puts forward a valuable aid for the early screening of subjects suspected of having SAHS.
Cao S, Rosenzweig I, Bilotta F, Jiang H, Xia M J Thorac Dis. 2024; 16(4):2654-2667.
PMID: 38738242 PMC: 11087644. DOI: 10.21037/jtd-24-310.
Association of Heart Rate Variability with Obstructive Sleep Apnea in Adults.
Lin Y, Chiang J, Lu C, Kao Y Medicina (Kaunas). 2023; 59(3).
PMID: 36984472 PMC: 10054532. DOI: 10.3390/medicina59030471.
Chiang J, Lin Y, Lu C, Kao Y Sleep Sci. 2022; 15(4):463-470.
PMID: 36419807 PMC: 9670768. DOI: 10.5935/1984-0063.20220068.
Validation of snoring detection using a smartphone app.
Chiang J, Lin Y, Lin C, Ting C, Chiang Y, Kao Y Sleep Breath. 2021; 26(1):81-87.
PMID: 33811634 PMC: 8857100. DOI: 10.1007/s11325-021-02359-3.
Akhter S, Abeyratne U, Swarnkar V, Hukins C J Clin Sleep Med. 2018; 14(6):991-1003.
PMID: 29852905 PMC: 5991962. DOI: 10.5664/jcsm.7168.