Introduction to Genetic Association Studies

Overview

Journal Cold Spring Harb Protoc

Specialties Biomedical Engineering
Pathology

Date 2012 Mar 3

PMID 22383645

Citations 85

Authors

Cathryn M Lewis

Jo Knight

Affiliations

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Abstract

Genetic association studies are used to find candidate genes or genome regions that contribute to a specific disease by testing for a correlation between disease status and genetic variation. This article provides a broad outline of the design and analysis of such studies, focusing on case-control studies in candidate genes or regions.

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