Comparison of the Genetic Structures Surrounding QnrA1 in Korean Enterobacter Cloacae and Chinese Escherichia Coli Strains Isolated in the Early 2000s: Evidence for QnrA Mobilization Via Inc HI2 Type Plasmid

Overview

Journal J Microbiol

Specialty Microbiology

Date 2012 Feb 28

PMID 22367953

Authors

Sang Hoon Han

Young Ah Kim

Minggui Wang

Yangsoon Lee

Hae-Sun Chung

Jong Hwa Yum

Dongeun Yong

Kyungwon Lee

June Myung Kim

Affiliations

Soon will be listed here.

Abstract

The flanking genetic structure of qnrA1 in Korean Enterobacter loacae was identical to that of the Chinese Escherichia coli strain, the first qnrA1-carrying strain reported in Asia. Analysis of restriction enzyme sites and Southern blot hybridization results showed that qnrA1 was transferred between E. cloacae and E. coli via Inc HI2 type plasmid.

References

Carattoli A, Bertini A, Villa L, Falbo V, Hopkins K, Threlfall E . Identification of plasmids by PCR-based replicon typing. J Microbiol Methods. 2005; 63(3):219-28. DOI: 10.1016/j.mimet.2005.03.018. View

Mammeri H, Van De Loo M, Poirel L, Martinez-Martinez L, Nordmann P . Emergence of plasmid-mediated quinolone resistance in Escherichia coli in Europe. Antimicrob Agents Chemother. 2004; 49(1):71-6. PMC: 538905. DOI: 10.1128/AAC.49.1.71-76.2005. View

Heuer H, Smalla K . Manure and sulfadiazine synergistically increased bacterial antibiotic resistance in soil over at least two months. Environ Microbiol. 2007; 9(3):657-66. DOI: 10.1111/j.1462-2920.2006.01185.x. View

Wang M, Tran J, Jacoby G, Zhang Y, Wang F, Hooper D . Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China. Antimicrob Agents Chemother. 2003; 47(7):2242-8. PMC: 161834. DOI: 10.1128/AAC.47.7.2242-2248.2003. View

Toleman M, Bennett P, Walsh T . Common regions e.g. orf513 and antibiotic resistance: IS91-like elements evolving complex class 1 integrons. J Antimicrob Chemother. 2006; 58(1):1-6. DOI: 10.1093/jac/dkl204. View

Jeong J, Yoon H, Kim E, Lee Y, Choi S, Kim N . Detection of qnr in clinical isolates of Escherichia coli from Korea. Antimicrob Agents Chemother. 2005; 49(6):2522-4. PMC: 1140518. DOI: 10.1128/AAC.49.6.2522-2524.2005. View

Park Y, Yu J, Lee S, Oh E, Woo G . Prevalence and diversity of qnr alleles in AmpC-producing Enterobacter cloacae, Enterobacter aerogenes, Citrobacter freundii and Serratia marcescens: a multicentre study from Korea. J Antimicrob Chemother. 2007; 60(4):868-71. DOI: 10.1093/jac/dkm266. View

Roche C, Boo T, Walsh F, Crowley B . Detection and molecular characterisation of plasmidic AmpC beta-lactamases in Klebsiella pneumoniae isolates from a tertiary-care hospital in Dublin, Ireland. Clin Microbiol Infect. 2008; 14(6):616-8. DOI: 10.1111/j.1469-0691.2008.01998.x. View

Cattoir V, Poirel L, Rotimi V, Soussy C, Nordmann P . Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J Antimicrob Chemother. 2007; 60(2):394-7. DOI: 10.1093/jac/dkm204. View

10.

Arduino S, Roy P, Jacoby G, Orman B, Pineiro S, Centron D . blaCTX-M-2 is located in an unusual class 1 integron (In35) which includes Orf513. Antimicrob Agents Chemother. 2002; 46(7):2303-6. PMC: 127297. DOI: 10.1128/AAC.46.7.2303-2306.2002. View

11.

Ma J, Zeng Z, Chen Z, Xu X, Wang X, Deng Y . High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. Antimicrob Agents Chemother. 2008; 53(2):519-24. PMC: 2630616. DOI: 10.1128/AAC.00886-08. View

12.

Poirel L, Villa L, Bertini A, Pitout J, Nordmann P, Carattoli A . Expanded-spectrum beta-lactamase and plasmid-mediated quinolone resistance. Emerg Infect Dis. 2007; 13(5):803-5. PMC: 2738457. DOI: 10.3201/eid1305.061293. View

13.

Nordmann P, Poirel L . Emergence of plasmid-mediated resistance to quinolones in Enterobacteriaceae. J Antimicrob Chemother. 2005; 56(3):463-9. DOI: 10.1093/jac/dki245. View

14.

Shen P, Jiang Y, Zhou Z, Zhang J, Yu Y, Li L . Complete nucleotide sequence of pKP96, a 67 850 bp multiresistance plasmid encoding qnrA1, aac(6')-Ib-cr and blaCTX-M-24 from Klebsiella pneumoniae. J Antimicrob Chemother. 2008; 62(6):1252-6. DOI: 10.1093/jac/dkn397. View

15.

Robicsek A, Jacoby G, Hooper D . The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect Dis. 2006; 6(10):629-40. DOI: 10.1016/S1473-3099(06)70599-0. View

16.

Arduino S, Catalano M, Orman B, Roy P, Centron D . Molecular epidemiology of orf513-bearing class 1 integrons in multiresistant clinical isolates from Argentinean hospitals. Antimicrob Agents Chemother. 2003; 47(12):3945-9. PMC: 296183. DOI: 10.1128/AAC.47.12.3945-3949.2003. View

17.

Eckert C, Gautier V, Arlet G . DNA sequence analysis of the genetic environment of various blaCTX-M genes. J Antimicrob Chemother. 2005; 57(1):14-23. DOI: 10.1093/jac/dki398. View