A Review of Obsessive-compulsive Disorder in Children and Adolescents

Overview

Journal Dialogues Clin Neurosci

Specialty Neurology

Date 2012 Jan 26

PMID 22275846

Citations 15

Authors

Bernard Boileau

Affiliations

Soon will be listed here.

Abstract

This article is a review of recent literature on obsessive-compulsive disorder in the pediatric population. Areas covered include: a brief historical perspective, clinical presentation in relation to symptoms found in different age groups, epidemiology, psychiatric comorbidity, etiology (with regards to genetics, neuroimaging, and familial factors), clinical course and prognosis, and treatment, with special emphasis on individual and family-based cognitive-behavioral therapy and psychopharmacology.

Citing Articles

Treatment and Family Involvement for Young Children with Obsessive-Compulsive Disorder: An Experimental Study.

Khenavandi Z Iran J Public Health. 2024; 52(12):2699-2700.

PMID: 38435766 PMC: 10903322. DOI: 10.18502/ijph.v52i12.14331.

Early Identification and Intervention in Pediatric Obsessive-Compulsive Disorder.

Liu X, Fan Q Brain Sci. 2023; 13(3).

PMID: 36979207 PMC: 10046131. DOI: 10.3390/brainsci13030399.

Therapeutic applications of transcutaneous auricular vagus nerve stimulation with potential for application in neurodevelopmental or other pediatric disorders.

Zhu S, Zhang X, Zhou M, Kendrick K, Zhao W Front Endocrinol (Lausanne). 2022; 13:1000758.

PMID: 36313768 PMC: 9596914. DOI: 10.3389/fendo.2022.1000758.

Determination of the relationship between major histocompatibility complex alleles and childhood onset obsessive-compulsive disorder.

Luleyap U, Karacaoglan G, Tahiroglu A, Yaman A, Pazarci P, Cetiner S Turk J Med Sci. 2022; 52(2):456-462.

PMID: 36161604 PMC: 10381195. DOI: 10.55730/1300-0144.5333.

Investıgation of vitamin D levels in obsessive-compulsive disorder.

Soyak H, Karakukcu C Indian J Psychiatry. 2022; 64(4):349-353.

PMID: 36060722 PMC: 9435610. DOI: 10.4103/indianjpsychiatry.indianjpsychiatry_26_22.

References

van Grootheest D, Bartels M, Cath D, Beekman A, Hudziak J, Boomsma D . Genetic and environmental contributions underlying stability in childhood obsessive-compulsive behavior. Biol Psychiatry. 2006; 61(3):308-15. DOI: 10.1016/j.biopsych.2006.05.035. View

Murphy T, Storch E, Turner A, Reid J, Tan J, Lewin A . Maternal history of autoimmune disease in children presenting with tics and/or obsessive-compulsive disorder. J Neuroimmunol. 2010; 229(1-2):243-7. PMC: 2991439. DOI: 10.1016/j.jneuroim.2010.08.017. View

Storch E, Lehmkuhl H, Ricketts E, Geffken G, Marien W, Murphy T . An open trial of intensive family based cognitive-behavioral therapy in youth with obsessive-compulsive disorder who are medication partial responders or nonresponders. J Clin Child Adolesc Psychol. 2010; 39(2):260-8. DOI: 10.1080/15374410903532676. View

Hirani V, Serpell L, Willoughby K, Neiderman M, Lask B . Typology of obsessive-compulsive symptoms in children and adolescents with anorexia nervosa. Eat Weight Disord. 2010; 15(1-2):e86-9. DOI: 10.1007/BF03325284. View

Bloch M, Sukhodolsky D, Dombrowski P, Panza K, Craiglow B, Landeros-Weisenberger A . Poor fine-motor and visuospatial skills predict persistence of pediatric-onset obsessive-compulsive disorder into adulthood. J Child Psychol Psychiatry. 2011; 52(9):974-83. PMC: 3625937. DOI: 10.1111/j.1469-7610.2010.02366.x. View

Peris T, Bergman R, Asarnow J, Langley A, McCracken J, Piacentini J . Clinical and cognitive correlates of depressive symptoms among youth with obsessive compulsive disorder. J Clin Child Adolesc Psychol. 2010; 39(5):616-26. PMC: 2950107. DOI: 10.1080/15374416.2010.501285. View

Lazaro L, Caldu X, Junque C, Bargallo N, Andres S, Morer A . Cerebral activation in children and adolescents with obsessive-compulsive disorder before and after treatment: a functional MRI study. J Psychiatr Res. 2008; 42(13):1051-9. DOI: 10.1016/j.jpsychires.2007.12.007. View

Stewart S, Geller D, Jenike M, Pauls D, Shaw D, Mullin B . Long-term outcome of pediatric obsessive-compulsive disorder: a meta-analysis and qualitative review of the literature. Acta Psychiatr Scand. 2004; 110(1):4-13. DOI: 10.1111/j.1600-0447.2004.00302.x. View

Lafleur D, Petty C, Mancuso E, McCarthy K, Biederman J, Faro A . Traumatic events and obsessive compulsive disorder in children and adolescents: is there a link?. J Anxiety Disord. 2011; 25(4):513-9. PMC: 3074033. DOI: 10.1016/j.janxdis.2010.12.005. View

10.

Mataix-Cols D, Nakatani E, Micali N, Heyman I . Structure of obsessive-compulsive symptoms in pediatric OCD. J Am Acad Child Adolesc Psychiatry. 2008; 47(7):773-778. DOI: 10.1097/CHI.0b013e31816b73c0. View

11.

Walitza S, Wendland J, Gruenblatt E, Warnke A, Sontag T, Tucha O . Genetics of early-onset obsessive-compulsive disorder. Eur Child Adolesc Psychiatry. 2010; 19(3):227-35. DOI: 10.1007/s00787-010-0087-7. View

12.

Micali N, Heyman I, Perez M, Hilton K, Nakatani E, Turner C . Long-term outcomes of obsessive-compulsive disorder: follow-up of 142 children and adolescents. Br J Psychiatry. 2010; 197(2):128-34. DOI: 10.1192/bjp.bp.109.075317. View

13.

Vloet T, Marx I, Kahraman-Lanzerath B, Zepf F, Herpertz-Dahlmann B, Konrad K . Neurocognitive performance in children with ADHD and OCD. J Abnorm Child Psychol. 2010; 38(7):961-9. DOI: 10.1007/s10802-010-9422-1. View

14.

Alexander A, Patel N, Southammakosane C, Mortensen M . Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an indication for tonsillectomy. Int J Pediatr Otorhinolaryngol. 2011; 75(6):872-3. DOI: 10.1016/j.ijporl.2011.03.006. View

15.

Masi G, Millepiedi S, Perugi G, Pfanner C, Berloffa S, Pari C . A naturalistic exploratory study of the impact of demographic, phenotypic and comorbid features in pediatric obsessive-compulsive disorder. Psychopathology. 2010; 43(2):69-78. DOI: 10.1159/000274175. View

16.

Geller D . Obsessive-compulsive and spectrum disorders in children and adolescents. Psychiatr Clin North Am. 2006; 29(2):353-70. DOI: 10.1016/j.psc.2006.02.012. View

17.

Ornstein T, Arnold P, Manassis K, Mendlowitz S, Schachar R . Neuropsychological performance in childhood OCD: a preliminary study. Depress Anxiety. 2009; 27(4):372-80. DOI: 10.1002/da.20638. View

18.

MacMaster F, ONeill J, Rosenberg D . Brain imaging in pediatric obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry. 2008; 47(11):1262-72. PMC: 2696312. DOI: 10.1097/CHI.0b013e318185d2be. View

19.

Ginsburg G, Kingery J, Drake K, Grados M . Predictors of treatment response in pediatric obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry. 2008; 47(8):868-78. DOI: 10.1097/CHI.0b013e3181799ebd. View

20.

Grant P, Song J, Swedo S . Review of the use of the glutamate antagonist riluzole in psychiatric disorders and a description of recent use in childhood obsessive-compulsive disorder. J Child Adolesc Psychopharmacol. 2010; 20(4):309-15. PMC: 2958461. DOI: 10.1089/cap.2010.0009. View