PJIE137 Carrying BlaCTX-M-62 is Closely Related to P271A Carrying BlaNDM-1

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2012 Jan 19

PMID 22252811

Citations 18

Authors

Sally R Partridge

Ian T Paulsen

Jonathan R Iredell

Affiliations

Soon will be listed here.

Abstract

Complete sequencing of pJIE137 revealed a backbone closely related to p271A, encoding a novel RepA protein but with a similar organization and up to ∼70% nucleotide identity to IncN plasmids. A region in pJIE137 resembling the IncN CUP regulon is mostly missing from p271A, presumably due to recombination. The class 1 In/Tn and ISEcp1-bla(CTX-M-62) transposition unit in pJIE137 and a putative transposon carrying bla(NDM-1) in p271A are inserted in different locations in the plasmid backbone.

Citing Articles

Insights into the genomic traits of Yersinia frederiksenii, Yersinia intermedia and Yersinia kristensenii isolated from diverse sources in Brazil.

Vilela F, Imori P, Allard M, Falcao J Antonie Van Leeuwenhoek. 2024; 117(1):86.

PMID: 38829455 DOI: 10.1007/s10482-024-01984-8.

IncFIB-4.1 and IncFIB-4.2 Single-Replicon Plasmids: Small Backbones with Large Accessory Regions.

Xu Y, Jing Y, Hu L, Cheng Q, Gao H, Zhang Z Infect Drug Resist. 2022; 15:1191-1203.

PMID: 35345473 PMC: 8957301. DOI: 10.2147/IDR.S332949.

Extended-Spectrum Beta-Lactamase Producing- Isolated From Irrigation Waters and Produce in Ecuador.

Montero L, Irazabal J, Cardenas P, Graham J, Trueba G Front Microbiol. 2021; 12:709418.

PMID: 34671324 PMC: 8521160. DOI: 10.3389/fmicb.2021.709418.

IncN1 ST7 Epidemic Plasmid Carrying blaIMP-4 in One ST85-Type Clinical Isolate with Porin Deficiency.

Sun M, Xiao W, Xu Q Infect Drug Resist. 2021; 14:3827-3835.

PMID: 34566416 PMC: 8458025. DOI: 10.2147/IDR.S330362.

Molecular Characterization of -Carrying in Henan Province of China.

Liu W, Dong H, Yan T, Liu X, Cheng J, Liu C Front Microbiol. 2021; 12:626160.

PMID: 33679645 PMC: 7925629. DOI: 10.3389/fmicb.2021.626160.

References

Poirel L, Lagrutta E, Taylor P, Pham J, Nordmann P . Emergence of metallo-β-lactamase NDM-1-producing multidrug-resistant Escherichia coli in Australia. Antimicrob Agents Chemother. 2010; 54(11):4914-6. PMC: 2976126. DOI: 10.1128/AAC.00878-10. View

Zong Z, Partridge S, Iredell J . ISEcp1-mediated transposition and homologous recombination can explain the context of bla(CTX-M-62) linked to qnrB2. Antimicrob Agents Chemother. 2010; 54(7):3039-42. PMC: 2897309. DOI: 10.1128/AAC.00041-10. View

Carattoli A, Bertini A, Villa L, Falbo V, Hopkins K, Threlfall E . Identification of plasmids by PCR-based replicon typing. J Microbiol Methods. 2005; 63(3):219-28. DOI: 10.1016/j.mimet.2005.03.018. View

Johnson T, Wannemuehler Y, Johnson S, Logue C, White D, Doetkott C . Plasmid replicon typing of commensal and pathogenic Escherichia coli isolates. Appl Environ Microbiol. 2007; 73(6):1976-83. PMC: 1828809. DOI: 10.1128/AEM.02171-06. View

Barton B, Harding G, Zuccarelli A . A general method for detecting and sizing large plasmids. Anal Biochem. 1995; 226(2):235-40. DOI: 10.1006/abio.1995.1220. View

Zong Z, Partridge S, Thomas L, Iredell J . Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool. Antimicrob Agents Chemother. 2008; 52(11):4198-202. PMC: 2573124. DOI: 10.1128/AAC.00107-08. View

Poirel L, Bonnin R, Nordmann P . Analysis of the resistome of a multidrug-resistant NDM-1-producing Escherichia coli strain by high-throughput genome sequencing. Antimicrob Agents Chemother. 2011; 55(9):4224-9. PMC: 3165296. DOI: 10.1128/AAC.00165-11. View

Walker G . Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli. Microbiol Rev. 1984; 48(1):60-93. PMC: 373003. DOI: 10.1128/mr.48.1.60-93.1984. View

Aziz R, Bartels D, Best A, DeJongh M, Disz T, Edwards R . The RAST Server: rapid annotations using subsystems technology. BMC Genomics. 2008; 9:75. PMC: 2265698. DOI: 10.1186/1471-2164-9-75. View

10.

Partridge S . Analysis of antibiotic resistance regions in Gram-negative bacteria. FEMS Microbiol Rev. 2011; 35(5):820-55. DOI: 10.1111/j.1574-6976.2011.00277.x. View

11.

Carattoli A, Aschbacher R, March A, Larcher C, Livermore D, Woodford N . Complete nucleotide sequence of the IncN plasmid pKOX105 encoding VIM-1, QnrS1 and SHV-12 proteins in Enterobacteriaceae from Bolzano, Italy compared with IncN plasmids encoding KPC enzymes in the USA. J Antimicrob Chemother. 2010; 65(10):2070-5. DOI: 10.1093/jac/dkq269. View

12.

Bush K . Alarming β-lactamase-mediated resistance in multidrug-resistant Enterobacteriaceae. Curr Opin Microbiol. 2010; 13(5):558-64. DOI: 10.1016/j.mib.2010.09.006. View

13.

Kamali-Moghaddam M, Sundstrom L . Transposon targeting determined by resolvase. FEMS Microbiol Lett. 2000; 186(1):55-9. DOI: 10.1111/j.1574-6968.2000.tb09081.x. View

14.

Delver E, Belogurov A . Organization of the leading region of IncN plasmid pKM101 (R46): a regulation controlled by CUP sequence elements. J Mol Biol. 1997; 271(1):13-30. DOI: 10.1006/jmbi.1997.1124. View

15.

Partridge S, Zong Z, Iredell J . Recombination in IS26 and Tn2 in the evolution of multiresistance regions carrying blaCTX-M-15 on conjugative IncF plasmids from Escherichia coli. Antimicrob Agents Chemother. 2011; 55(11):4971-8. PMC: 3195058. DOI: 10.1128/AAC.00025-11. View

16.

Santini J, Stanisich V . Both the fipA gene of pKM101 and the pifC gene of F inhibit conjugal transfer of RP1 by an effect on traG. J Bacteriol. 1998; 180(16):4093-101. PMC: 107403. DOI: 10.1128/JB.180.16.4093-4101.1998. View

17.

Wilkins B . Plasmid promiscuity: meeting the challenge of DNA immigration control. Environ Microbiol. 2002; 4(9):495-500. DOI: 10.1046/j.1462-2920.2002.00332.x. View

18.

Garcillan-Barcia M, Alvarado A, de la Cruz F . Identification of bacterial plasmids based on mobility and plasmid population biology. FEMS Microbiol Rev. 2011; 35(5):936-56. DOI: 10.1111/j.1574-6976.2011.00291.x. View

19.

Partridge S, Ellem J, Tetu S, Zong Z, Paulsen I, Iredell J . Complete sequence of pJIE143, a pir-type plasmid carrying ISEcp1-blaCTX-M-15 from an Escherichia coli ST131 isolate. Antimicrob Agents Chemother. 2011; 55(12):5933-5. PMC: 3232798. DOI: 10.1128/AAC.00639-11. View