Determinants of Food Allergy

Overview

Journal Immunol Allergy Clin North Am

Specialty Allergy & Immunology

Date 2012 Jan 17

PMID 22244230

Citations 17

Authors

Madhan Masilamani

Scott Commins

Wayne Shreffler

Affiliations

Soon will be listed here.

Abstract

Food allergy is an emerging epidemic in the United States and the Western world. The determination of factors that make certain foods allergenic is still not clearly understood. Only a tiny fraction of thousands of proteins and other molecules is responsible for inducing food allergy. In this review, the authors present 3 examples of food allergies with disparate clinical presentations: peanut, soy, and mammalian meat. The potential relationships between allergen structure and function, emphasizing the importance of cross-reactive determinants, immunoglobulin E antibodies to the oligosaccharides, and the immune responses induced in humans are discussed.

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