Determinants of Vitamin D Status Among Overweight and Obese Puerto Rican Adults
Overview
Nutritional Sciences
Affiliations
Background/aims: Low vitamin D status is highly prevalent worldwide, and the major determinants are sun exposure and vitamin D intake. We aimed to measure vitamin D status in a sample of overweight/obese adults in Puerto Rico, an area with plenty of sun exposure, and relate it to vitamin D intake, sun exposure and body composition.
Methods: Serum 25(OH)D levels (liquid chromatography-tandem mass spectrometry), body weight and fat (bioimpedance), vitamin D intake and sun exposure (questionnaires) were assessed. Analysis included age-adjusted correlations and multivariate regression.
Results: In 98 subjects (66% females; 40-65 years), median serum 25(OH)D levels were 30.7 ng/ml (25-75th percentile 25.0-37.3); 55% had levels >30 ng/ml, 31% had levels between 20 and 30 ng/ml and 14% had levels <20 ng/ml. Total vitamin D intake was 180 IU/day (45-615), and the sun exposure score was 22 (17-27). After adjusting for gender, 25(OH)D levels were significantly correlated with vitamin D intake (r = 0.24, p = 0.018), the sum of sun exposure and vitamin D intake indices (r = 0.34, p = 0.001) and percent body fat (r = -0.25, p = 0.01). After adjusting for age, gender and percent body fat, the sum of sun exposure and vitamin D intake indices remained statistically associated with 25(OH)D levels (β = 1.5, p < 0.01).
Conclusions: In this group of overweight and obese individuals, 25(OH)D was significantly related to vitamin D intake, sun exposure and vitamin D intake indices and percent body fat.
Zhang N, Wang Y, Li W, Wang Y, Zhang H, Xu D Sci Rep. 2025; 15(1):6454.
PMID: 39987347 PMC: 11846893. DOI: 10.1038/s41598-025-90785-8.
Lee M Nutrients. 2025; 17(3).
PMID: 39940444 PMC: 11820181. DOI: 10.3390/nu17030586.
The Association of Obesity and the Antiaging Humoral Factor Klotho in Middle-Aged and Older Adults.
Orces C ScientificWorldJournal. 2022; 2022:7274858.
PMID: 36061981 PMC: 9433301. DOI: 10.1155/2022/7274858.
Ortiz-Sanchez C, Encarnacion-Medina J, Vergne R, Padilla L, Matta J Int J Mol Sci. 2020; 21(18).
PMID: 32961801 PMC: 7555346. DOI: 10.3390/ijms21186880.
Orces C Cureus. 2019; 11(9):e5721.
PMID: 31720189 PMC: 6823089. DOI: 10.7759/cureus.5721.